Results 71 to 80 of about 5,854,935 (299)

A Site‐Aware Representation Learning Framework For Unified Molecular Interaction Modeling and Generative Design

open access: yesAdvanced Science, EarlyView.
MolDBG is a site‐aware, sequence‐only framework that unifies drug‐target affinity prediction, binding‐site identification, and affinity‐conditioned molecular generation for structured proteins. Guided by multi‐task binding‐site supervision, it aligns interaction‐critical residues before learning drug‐target representations and simultaneously infers ...
Gang Luo   +6 more
wiley   +1 more source

Predictions of lightning activity at Neptune

open access: yesGeophysical Research Letters, 1989
Spacecraft observations of the seven innermost planets suggest that lightning is present on all planets with dense atmospheres. Thus lightning may be expected to occur on Neptune as well. Based on the level of lightning activity observed on Jupiter and on the assumption that the lightning energy dissipation rate is a constant fraction of the ...
openaire   +1 more source

Lightning activity in the eastern Mediterranean region [PDF]

open access: yesJournal of Geophysical Research: Atmospheres, 2005
Twenty days of lightning activity recorded during winter 2002–2003 in the Mediterranean region with significant rain accumulation in Greece were studied on the basis of the measurements of the UK Met Office long‐range VLF sferics Arrival Time Difference (ATD) system and the spaceborne NASA Lightning Imaging Sensor (LIS) sensor onboard the Tropical ...
E. Defer, K. Lagouvardos, V. Kotroni
openaire   +1 more source

Surface Neuronal‐Like Structuring of High‐Strength CFRP for Enhanced Electromagnetic Interference Shielding

open access: yesAdvanced Science, EarlyView.
This study elucidates the microstructural evolution at the material interface of Ni‐plated plain‐weave carbon fiber fabric following vacuum heat treatment at 500°C–900°C under different current densities, as well as the mechanism underlying the synergistic enhancement of electromagnetic shielding and ductility.
Wei Cheng   +7 more
wiley   +1 more source

Thunderstorm total lightning activity behavior associated with transmission line trip events of power system

open access: yesnpj Climate and Atmospheric Science
High-voltage transmission lines are susceptible targets for lightning strikes. It is an interesting topic how the trip event of transmission line is related to the area, location, and intensity of thunderstorms occurring at that time and that place ...
Muzi Li   +6 more
doaj   +1 more source

Tau Aggregate Imaging and Transcriptomics of Alzheimer's Disease Brain at Different Stages of Disease

open access: yesAdvanced Science, EarlyView.
The protein aggregates and gene expression in the middle temporal gyrus (MTG) and somatosensory cortex (SOM) of the postmortem brains of 13 Alzheimer's disease patients were studied in detail, revealing that small hyperphosphorylated tau aggregates increase with Braak stage driven by microglial inflammation.
Elizabeth A. English   +9 more
wiley   +1 more source

YTHDC1 Orchestrates Glucose and Glutamate Rewiring to Overcome Lethal Metabolic Stress in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
Lai et al. find that m6A reader YTHDC1 is specifically overexpressed in triple‐negative breast cancer (TNBC) and orchestrates glucose and glutamine metabolism in an m6A‐dependent manner to confer robust adaptability to lethal metabolic stress. Leveraging YTHDC1 knockdown‐induced metabolic vulnerability, an ATF4 mRNA‐targeted nanotherapy is developed to
Zheng‐Hao Lai   +12 more
wiley   +1 more source

Application of 3D scanning technology in Royal Malaysian Air Force Industrial Revolution 4.0‐based aircraft maintenance

open access: yesIET Networks, EarlyView., 2022
Abstract 3D scanning is rapidly becoming a key maintenance tool. Aerospace was a pioneer in adopting 3D scanning technology because aircraft manufacture and maintenance require precision. Monitoring deterioration, removing components for maintenance, and verifying covert operations are not practical or helpful without technology.
T. Nanthakumaran Thulasy   +4 more
wiley   +1 more source

Hippocampal Seizure‐Related Burden is Associated with Accelerated Long‐Term Forgetting in Focal Epilepsy

open access: yesAnnals of Neurology, EarlyView.
Objective Memory impairment is a frequent comorbidity of focal epilepsy, incompletely explained by seizure frequency or structural pathology. Ictal and postictal hippocampal dysfunction disrupt memory processes, but their cumulative impact remains poorly quantified.
Ionuț‐Flavius Bratu   +5 more
wiley   +1 more source

Detection of a Squall Line Event by DDW1 Total Lightning Locating System

open access: yes应用气象学报
At present, China's meteorological departments are gradually upgrading their lightning location networks from ADTD (Advanced TOA and Direction) system to DDW1 Total Lightning Location System.
Xu Shulin   +8 more
doaj   +1 more source

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