Results 181 to 190 of about 19,790 (306)

Impact of Air Pollutants on Lightning Activities in Kathmandu, Nepal. [PDF]

open access: yesScientificWorldJournal
Adhikari PB   +3 more
europepmc   +1 more source

Human IDO2 exhibits unique binding affinities distinct to those of human IDO1

open access: yesThe FEBS Journal, EarlyView.
Although indoleamine 2,3‐dioxygenase 2 (IDO2) is highly homologous to IDO1, it displays markedly lower catalytic activity. We found that IDO2 binds L‐tryptophan (L‐Trp) in a flipped orientation stabilized by the IDO2‐specific residue His143. Replacement of His143 with the IDO1‐equivalent tyrosine restored an IDO1‐like binding mode and increased ...
Shunsuke Nogi   +8 more
wiley   +1 more source

Unraveling in vitro phase separation and aggregation properties of the structured region of FMRP and the impact of Fragile X syndrome‐linked mutations

open access: yesThe FEBS Journal, EarlyView.
Fragile X messenger ribonucleoprotein 1 (FMRP) is a multidomain RNA‐binding protein associated with Fragile X Syndrome (FXS). We found that its N‐terminal structured region has an intrinsic propensity to undergo liquid–liquid phase separation and fibril formation. FXS‐associated mutations perturb protein stability and aggregation propensity, suggesting
Flavia Catalano   +10 more
wiley   +1 more source

Unraveling the active site cover of coproheme decarboxylase from Listeria monocytogenes

open access: yesThe FEBS Journal, EarlyView.
During heme biosynthesis in Gram‐positive bacteria, coproheme decarboxylase (ChdC) catalyzes the conversion of four‐propionate substrate coproheme to the two propionate product heme b. Its active site is universally covered by a flexible linking loop. This study identifies an important histidine residue, which stabilizes the loop in a ChdC homolog.
Nikolaus Falb   +4 more
wiley   +1 more source

A case-aware feature modulation framework for defect classification in power lines. [PDF]

open access: yesSci Rep
Ezzulddin NF   +4 more
europepmc   +1 more source

Turbulence and particle dynamics in volcanic clouds in humid atmospheres. [PDF]

open access: yesSci Rep
Zapata F   +4 more
europepmc   +1 more source

Natural disaster risk salience and the strategic appointment of directors with sustainability expertise

open access: yesJournal of Financial Research, EarlyView.
Abstract This article examines how salient sustainability risks from near‐miss natural disasters influence board composition. Using a difference‐in‐differences design, I find that firms located in counties neighboring disaster‐affected areas significantly increase the presence of directors with sustainability expertise following the disaster.
Bo Wang
wiley   +1 more source

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