Results 171 to 180 of about 2,833,637 (301)

Unraveling in vitro phase separation and aggregation properties of the structured region of FMRP and the impact of Fragile X syndrome‐linked mutations

open access: yesThe FEBS Journal, EarlyView.
Fragile X messenger ribonucleoprotein 1 (FMRP) is a multidomain RNA‐binding protein associated with Fragile X Syndrome (FXS). We found that its N‐terminal structured region has an intrinsic propensity to undergo liquid–liquid phase separation and fibril formation. FXS‐associated mutations perturb protein stability and aggregation propensity, suggesting
Flavia Catalano   +10 more
wiley   +1 more source

Unraveling the active site cover of coproheme decarboxylase from Listeria monocytogenes

open access: yesThe FEBS Journal, EarlyView.
During heme biosynthesis in Gram‐positive bacteria, coproheme decarboxylase (ChdC) catalyzes the conversion of four‐propionate substrate coproheme to the two propionate product heme b. Its active site is universally covered by a flexible linking loop. This study identifies an important histidine residue, which stabilizes the loop in a ChdC homolog.
Nikolaus Falb   +4 more
wiley   +1 more source

Imaging Earth's subsurface with thunderstorm-generated seismic waves. [PDF]

open access: yesSci Adv
Roth N   +5 more
europepmc   +1 more source

Mechanisms and scales in modeling forest responses to changing disturbance regimes. [PDF]

open access: yesNew Phytol
Xu X   +11 more
europepmc   +1 more source

“There's Pressure to Use Standard English”: Lingering Linguicism in the Work of Signed Language Interpreters

open access: yesInternational Journal of Applied Linguistics, EarlyView.
ABSTRACT Applied linguistics and interpreting have much in common; however, the education of signed language interpreters in the States provides barely any applied linguistics training. Linguistic racism (linguicism) frames the education and evaluation of sign language interpreters.
Sharon Grigsby Hill
wiley   +1 more source

Artificial Intelligence and Nursing: Freedom From the Mundane or Subservience to a New Nobility

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aim To explore the notion of post‐humanism and the impact of artificial intelligence (AI) on society, nursing and healthcare. Design Discursive paper. Methods Critical reflection on concepts relating to post‐humanism and the impact of AI, sourced from contemporary and established literature. Data Sources Information was drawn from a wide range
David A. Richards
wiley   +1 more source

Natural disaster risk salience and the strategic appointment of directors with sustainability expertise

open access: yesJournal of Financial Research, EarlyView.
Abstract This article examines how salient sustainability risks from near‐miss natural disasters influence board composition. Using a difference‐in‐differences design, I find that firms located in counties neighboring disaster‐affected areas significantly increase the presence of directors with sustainability expertise following the disaster.
Bo Wang
wiley   +1 more source

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