Results 171 to 180 of about 7,343 (289)

Leadership and Accountability in Faith‐Based Institutions: Evidence From UK Mosques

open access: yesFinancial Accountability &Management, EarlyView.
ABSTRACT This study investigates accountability in religious institutions on the basis of evidence obtained from interviews with relevant parties in UK mosques. We mobilize prior theoretical contention regarding servant leadership and constraints on personal accountability to expose perceptions of seriously deficient discharge outcomes.
Umair Riaz   +3 more
wiley   +1 more source

Human IDO2 exhibits unique binding affinities distinct to those of human IDO1

open access: yesThe FEBS Journal, EarlyView.
Although indoleamine 2,3‐dioxygenase 2 (IDO2) is highly homologous to IDO1, it displays markedly lower catalytic activity. We found that IDO2 binds L‐tryptophan (L‐Trp) in a flipped orientation stabilized by the IDO2‐specific residue His143. Replacement of His143 with the IDO1‐equivalent tyrosine restored an IDO1‐like binding mode and increased ...
Shunsuke Nogi   +8 more
wiley   +1 more source

Unraveling in vitro phase separation and aggregation properties of the structured region of FMRP and the impact of Fragile X syndrome‐linked mutations

open access: yesThe FEBS Journal, EarlyView.
Fragile X messenger ribonucleoprotein 1 (FMRP) is a multidomain RNA‐binding protein associated with Fragile X Syndrome (FXS). We found that its N‐terminal structured region has an intrinsic propensity to undergo liquid–liquid phase separation and fibril formation. FXS‐associated mutations perturb protein stability and aggregation propensity, suggesting
Flavia Catalano   +10 more
wiley   +1 more source

Unraveling the active site cover of coproheme decarboxylase from Listeria monocytogenes

open access: yesThe FEBS Journal, EarlyView.
During heme biosynthesis in Gram‐positive bacteria, coproheme decarboxylase (ChdC) catalyzes the conversion of four‐propionate substrate coproheme to the two propionate product heme b. Its active site is universally covered by a flexible linking loop. This study identifies an important histidine residue, which stabilizes the loop in a ChdC homolog.
Nikolaus Falb   +4 more
wiley   +1 more source

McMahon Score as a predictor of mortality in lightning-associated rhabdomyolysis. [PDF]

open access: yesBMC Nephrol
Şen A   +9 more
europepmc   +1 more source

Morphological, structural and physical characterization of commercially available low voltage ZnO-based varistors. [PDF]

open access: yesSci Rep
Wójcik K   +6 more
europepmc   +1 more source

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