Results 111 to 120 of about 23,718 (250)

Discovery of a Novel γ‐Glutamylcyclotransferase Inhibitor Plumbagin by Luminescence‐Based High‐Throughput Screening

Cancer Science, Volume 117, Issue 6, Page 1713-1723, June 2026.
A cell‐based high‐throughput screening system utilizing the luminescent probe LISA‐103 was developed to monitor γ‐glutamylcyclotransferase (GGCT) activity in cancer cells. Through this assay, plumbagin was identified as a novel GGCT inhibitor that induces cell cycle arrest and suppresses cancer cell growth. ABSTRACT γ‐Glutamylcyclotransferase (GGCT) is
Keiko Taniguchi, Yukie Nohara, Mano Horinaka, Kozue Nose, Masaya Mori, Hiromi Ii, Hiroko Kawakami, Kazuto Yano, Susumu Nakata, Taku Yoshiya, Toshiyuki Sakai   +10 more
wiley   +1 more source

Integrated Network Pharmacology and Machine Learning to Reveal the Mechanisms of Schisandrin A Against Triple‐Negative Breast Cancer

Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT This study aimed to elucidate the mechanism of action of Schisandrin A in the intervention of triple‐negative breast cancer (TNBC). Through the application of network pharmacology and the integration of targets from multiple databases, the research identified 128 overlapping targets between Schisandrin A and TNBC.
Meng Xu, Yingchun Zhang, Rubing Mei, Tingting Xue, Hongning Cai, Yu Zhou, Jianfang Guo   +6 more
wiley   +1 more source

Modeling of flaxseed protein, oil content, linoleic acid, and lignan content prediction based on hyperspectral imaging

Frontiers in Plant Science
Protein, oil content, linoleic acid, and lignan are several key indicators for evaluating the quality of flaxseed. In order to optimize the testing methods for flaxseed’s nutritional quality and enhance the efficiency of screening high-quality flax ...
Dongyu Zhu, Junying Han, Chengzhong Liu, Jianping Zhang, Yanni Qi   +4 more
doaj   +1 more source

Lignan compound isolated from n-Hexane extract myristica fragrans Houtt root as antioxidant and antitumor activities against MCF-7 cell lines data

, 2020
Binawati Ginting, Nurdin Saidi, MURNIANA MURNIANA, Mustanir Mustanir, Maulidna, Partomuan Simanjuntak   +5 more
openalex   +1 more source

Investigating Dietary Polyphenol Intake in the Australian Population: Results From the 2011–12 National Nutrition and Physical Activity Survey

Journal of Human Nutrition and Dietetics, Volume 39, Issue 3, June 2026.
ABSTRACT Introduction There is a lack of detailed polyphenol intake data collected at the national level, both in Australia and globally. Hence, the aim of this study was to estimate the intake of total polyphenols, polyphenol classes, and polyphenol subclasses in a nationally representative sample of Australians across the lifespan. Methods Polyphenol
Elizabeth Gamage, Mohammadreza Mohebbi, Mojtaba Lotfaliany, Deborah N. Ashtree, Melissa M. Lane, Rebecca Orr, Felice N. Jacka, Wolfgang Marx   +7 more
wiley   +1 more source

Separation of diastereoisomers of podophyllum lignans by micellar electrokinetic chromatography

, 2002
Shu-Hui Liu, Xuan Tian, Xingguo Chen, Zhide Hu   +3 more
openalex   +2 more sources

Saururus cernuus lignans—Potent small molecule inhibitors of hypoxia-inducible factor-1

, 2005
Chowdhury Faiz Hossain, Yong-Pil Kim, Scott R. Baerson, Lei Zhang, Richard K. Bruick, Kaleem A. Mohammed, Ameeta K. Agarwal, Dale G. Nagle, Yu-Dong Zhou   +8 more
openalex   +2 more sources

Pharmacokinetic Compatibility of Ginsenosides and Schisandra Lignans in Shengmai-san: From the Perspective of P-Glycoprotein

, 2014
Yan Liang, Yuanyuan Zhou, Jingwei Zhang, Tai Rao, Lijun Zhou, Xing Rong, Qian Wang, Hanxu Fu, Kun Hao, Lin Xie, Guangji Wang   +10 more
openalex   +2 more sources

Inhibition of the Discoloration of Yellowtail Dark Muscle by Lignan [PDF]

, 2010
Satoshi Yamauchi, Taro Kishida, Takuya Sugahara, Manami YAMAWAKI, Sogo Nishimoto, Yoh-ichi SHINOMIYA, Toru Yamamoto   +6 more
openalex   +1 more source

FLAVONOIDS AND LIGNANS FROM THE LEAVES OF NEPETA MULTIFIDA (LAMIACEAE) AND THEIR BIOAC-TIVITY

, 2022
N. I. Kashchenko, Д. Н. Оленников   +1 more
openalex   +2 more sources