Results 111 to 120 of about 21,869 (236)
Sesame Immunotherapy: A Systematic Review and Narrative Synthesis
ABSTRACT Sesame allergy is associated with severe allergic reactions, low rates of spontaneous resolution, and significant psychosocial burden. Current management relies on strict avoidance and emergency treatment. Allergen‐specific immunotherapy, particularly oral immunotherapy (OIT), has emerged as a potential disease‐modifying approach, but evidence
Joanna Zielińska +4 more
wiley +1 more source
The gut microbial ecosystem underlies physiological relationships between the gut and distal organs. Mechanisms remain elusive but rely at least partially on the production of a diverse set of absorbable metabolites and host gene expression regulation ...
Diana Wu +2 more
doaj +1 more source
Computational drug discovery integrates molecular docking, molecular dynamics simulations, and translational clinical targeting to identify next‐generation therapeutics that overcome endocrine resistance in ER‐positive breast cancer. Combined with multi‐omics, artificial intelligence, and biomarker‐guided precision oncology, these approaches accelerate
Emmanuel Ifeanyi Obeagu, Yaregal Asres
wiley +1 more source
Cytotoxic Lignan Esters from Cinnamomum osmophloeum
! The bark and roots of Cinnamomum osmophloeum are widely used in Taiwan as spice substitutes for C. cassia. We have isolated three novel lignan esters, one dibenzylbutane-type ligan ester [9,9'di- O-feruloyl-(+)-5,5'-dimethoxy secoisolariciresinol (3 ...
Huang, Y.H. +8 more
core +1 more source
EBND alone upregulates neurofilament expression but does not induce neurite outgrowth in PC12 cells. With suboptimal NGF, EBND synergistically promotes neuronal differentiation via the TrkA‐ERK1/2‐CREB‐BDNF pathway. This effect is blocked by the TrkA inhibitor GW441756, confirming a TrkA‐dependent mechanism.
Wen Zhang +9 more
wiley +1 more source
COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING LIGNAN COMPOUND
The present invention relates to a pharmaceutical composition for preventing, ameliorating, or treating cancer. More specifically, the present invention relates to a pharmaceutical composition for preventing or treating cancer including a lignan compound
김정희 +5 more
core
Postbiotics Unveiled: The Next Emerging Trend in Functional Foods
The graphical abstract shows different postbiotic production techniques, such as sonication, fermentation, heat inactivation, high‐pressure processing, dehydration, pH modification, and omic technologies. Additionally, it highlights the emerging health benefits and applications of postbiotics, including immune modulation, gut–brain axis regulation ...
Zoha Wahid +4 more
wiley +1 more source
Anti‐inflammatory and cytotoxic properties of kānuka (Kunzea ericoides) subcritical water extract
Abstract BACKGROUND Kānuka (Kunzea ericoides) is a medicinal plant native to New Zealand with numerous therapeutic benefits due to its rich bioactive profile. Although several in vitro studies have shown promising anti‐inflammatory activity, substantial evidence elucidating its underlying inflammatory regulatory mechanism and evaluating its cytotoxic ...
Indhuja Devadass +2 more
wiley +1 more source
Background and aim: Plant lignans are metabolised by the colonic micro-flora to the mammalian lignans enterodiol. and enterolactone, which are hypothesized to be cardioprotective.
Bügel, Susanne Gjedsted +7 more
core +1 more source
The ethanolic leaf extract of Mouriri elliptica exhibited antibacterial and antibiofilm activities against multidrug‐resistant clinical isolates and enhanced the activity of ampicillin. Its diverse chemical profile and low acute toxicity support this Cerrado species as a promising source of natural antibacterial adjuvants. ABSTRACT Bacterial resistance
Talita Vilalva Freire +9 more
wiley +1 more source

