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Lignans and Their Derivatives from Plants as Antivirals

Molecules, 2020
Lignans are widely produced by various plant species; they are a class of natural products that share structural similarity. They usually contain a core scaffold that is formed by two or more phenylpropanoid units. Lignans possess diverse pharmacological
Qinghua Cui, Ruikun Du, Haiyan Liu
exaly   +3 more sources

Molecular Mechanisms of Lignans in Lowering Blood Pressure and Anti-Obesity Effects: A Review [PDF]

Foods
Lignans are naturally occurring compounds found in a wide variety of plant species, including flaxseed, soybean, pumpkin seed, broccoli, sesame seed, and some berries.
Gitishree Das, Sandra Gonçalves, José Basilio Heredia, Nayely Leyva-López, Anabela Romano, Spiros Paramithiotis, Han-Seung Shin, Jayanta Kumar Patra   +7 more
doaj   +2 more sources

Lignans of Sesame (Sesamum indicum L.): A Comprehensive Review

Molecules, 2021
Major lignans of sesame sesamin and sesamolin are benzodioxol--substituted furofurans. Sesamol, sesaminol, its epimers, and episesamin are transformation products found in processed products.
Mebeaselassie Andargie, Maria Vinas, Anna Rathgeb, Evelyn Möller, Petr Karlovsky   +4 more
doaj   +1 more source

Biological functions of lignans in plants

Agriculture, 2021
Naturally occurring lignans are present in seeds, nuts, cereals, vegetables, and fruits. Lignans play various roles in plants and their multipurpose functions of different organisms including humans is considerable.
Ražná Katarína, Nôžková Janka, Vargaová Angéla, Harenčár Ľubomír, Bjelková Marie   +4 more
doaj   +1 more source

Evaluation of the Antioxidant and Antiradical Properties of Some Phyto and Mammalian Lignans

Molecules, 2021
In this study, the antioxidant and antiradical properties of some phyto lignans (nordihydroguaiaretic acid, secoisolariciresinol, secoisolariciresinol diglycoside, and α-(-)-conidendrin) and mammalian lignans (enterodiol and enterolactone) were examined ...
Leyla Polat Kose, İlhami Gulcin
doaj   +1 more source

Lignans from Bursera fagaroides: Chemistry, Pharmacological Effects and Molecular Mechanism. A Current Review

Life, 2021
Bursera fagaroides is a medicinal tree endemic to México, it belongs to the Burseraceae family and has proven antitumor activity. Modern research, performed principally with the bark extracts, have indicated that lignans are the main active constituents ...
Mayra Antúnez-Mojica, Antonio Romero-Estrada, Israel Hurtado-Díaz, Alfonso Miranda-Molina, Laura Alvarez   +4 more
doaj   +1 more source

Characterization of three naturally occurring lignans, sesamol, sesamolin, and sesamin, as potent inhibitors of human cytochrome P450 46A1: Implications for treating excitatory neurotoxicity

Frontiers in Pharmacology, 2022
CYP46A1 is a brain-specific enzyme responsible for cholesterol homeostasis. Inhibition of CYP46A1 activity serves as a therapeutic target for excitatory neurotoxicity.
Jie Du, Jie Du, Xiaodong Chen, Xiaodong Chen, Yongshun Zhao, Tingting Zhao, Tingting Zhao, Dalong Wang, Dalong Wang, Zujia Chen, Zujia Chen, Changyuan Wang, Changyuan Wang, Qiang Meng, Qiang Meng, Jialin Yao, Jialin Yao, Huijun Sun, Huijun Sun, Kexin Liu, Kexin Liu, Jingjing Wu, Jingjing Wu   +22 more
doaj   +1 more source

Antimicrobial Activity of Hydroxymatairesinol (HMR) Lignan#

Iraqi Journal of Pharmaceutical Sciences, 2017
Lignans are natural products widely distributed in the plant kingdom. They are composed of two β-β-linked phenylpropane (shikimate-derived biogenetic subunits).
Widad M.K. Al-Ani, Fitua M. Aziz
doaj   +3 more sources

Insight into the Influence of Cultivar Type, Cultivation Year, and Site on the Lignans and Related Phenolic Profiles, and the Health-Promoting Antioxidant Potential of Flax (Linum usitatissimum L.) Seeds

Molecules, 2018
Flaxseeds are a functional food representing, by far, the richest natural grain source of lignans, and accumulate substantial amounts of other health beneficial phenolic compounds (i.e., flavonols, hydroxycinnamic acids).
Laurine Garros, Samantha Drouet, Cyrielle Corbin, Cédric Decourtil, Thibaud Fidel, Julie Lebas de Lacour, Emilie A. Leclerc, Sullivan Renouard, Duangjai Tungmunnithum, Joël Doussot, Bilal Haider Abassi, Benoit Maunit, Éric Lainé, Ophélie Fliniaux, François Mesnard, Christophe Hano   +15 more
doaj   +1 more source

Lignans: a versatile source of anticancer drugs

Beni-Suef University Journal of Basic and Applied Sciences, 2022
Background Cancer is considered as the second deadliest disease globally. Plants have continuously offered unique secondary metabolites with remarkable biological applications.
Minky Mukhija, Bhuwan Chandra Joshi, Partha Sarathi Bairy, Anurag Bhargava, Archana N. Sah   +4 more
doaj   +1 more source