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Molecular Mechanisms of Lignans in Lowering Blood Pressure and Anti-Obesity Effects: A Review [PDF]

open access: yesFoods
Lignans are naturally occurring compounds found in a wide variety of plant species, including flaxseed, soybean, pumpkin seed, broccoli, sesame seed, and some berries.
Gitishree Das   +7 more
doaj   +2 more sources

Lignans and Their Derivatives from Plants as Antivirals

open access: yesMolecules, 2020
Lignans are widely produced by various plant species; they are a class of natural products that share structural similarity. They usually contain a core scaffold that is formed by two or more phenylpropanoid units. Lignans possess diverse pharmacological
Qinghua Cui, Ruikun Du, Miaomiao Liu
exaly   +3 more sources

Biological functions of lignans in plants

open access: yesAgriculture, 2021
Naturally occurring lignans are present in seeds, nuts, cereals, vegetables, and fruits. Lignans play various roles in plants and their multipurpose functions of different organisms including humans is considerable.
Ražná Katarína   +4 more
doaj   +1 more source

Lignans of Sesame (Sesamum indicum L.): A Comprehensive Review

open access: yesMolecules, 2021
Major lignans of sesame sesamin and sesamolin are benzodioxol--substituted furofurans. Sesamol, sesaminol, its epimers, and episesamin are transformation products found in processed products.
Mebeaselassie Andargie   +4 more
doaj   +1 more source

Evaluation of the Antioxidant and Antiradical Properties of Some Phyto and Mammalian Lignans

open access: yesMolecules, 2021
In this study, the antioxidant and antiradical properties of some phyto lignans (nordihydroguaiaretic acid, secoisolariciresinol, secoisolariciresinol diglycoside, and α-(-)-conidendrin) and mammalian lignans (enterodiol and enterolactone) were examined ...
Leyla Polat Kose, İlhami Gulcin
doaj   +1 more source

Lignans from Bursera fagaroides: Chemistry, Pharmacological Effects and Molecular Mechanism. A Current Review

open access: yesLife, 2021
Bursera fagaroides is a medicinal tree endemic to México, it belongs to the Burseraceae family and has proven antitumor activity. Modern research, performed principally with the bark extracts, have indicated that lignans are the main active constituents ...
Mayra Antúnez-Mojica   +4 more
doaj   +1 more source

Characterization of three naturally occurring lignans, sesamol, sesamolin, and sesamin, as potent inhibitors of human cytochrome P450 46A1: Implications for treating excitatory neurotoxicity

open access: yesFrontiers in Pharmacology, 2022
CYP46A1 is a brain-specific enzyme responsible for cholesterol homeostasis. Inhibition of CYP46A1 activity serves as a therapeutic target for excitatory neurotoxicity.
Jie Du   +22 more
doaj   +1 more source

Inhibitory Effects of Schisandra Lignans on Cytochrome P450s and Uridine 5′-Diphospho-Glucuronosyl Transferases in Human Liver Microsomes

open access: yesPharmaceutics, 2021
Schisandra chinensis has been widely used as a traditional herbal medicine to treat chronic coughs, fatigue, night sweats, and insomnia. Numerous bioactive components including lignans have been identified in this plant.
Hyung-Ju Seo   +7 more
doaj   +1 more source

Antimicrobial Activity of Hydroxymatairesinol (HMR) Lignan#

open access: yesIraqi Journal of Pharmaceutical Sciences, 2017
Lignans are natural products widely distributed in the plant kingdom. They are composed of two β-β-linked phenylpropane (shikimate-derived biogenetic subunits).
Widad M.K. Al-Ani, Fitua M. Aziz
doaj   +3 more sources

Insight into the Influence of Cultivar Type, Cultivation Year, and Site on the Lignans and Related Phenolic Profiles, and the Health-Promoting Antioxidant Potential of Flax (Linum usitatissimum L.) Seeds

open access: yesMolecules, 2018
Flaxseeds are a functional food representing, by far, the richest natural grain source of lignans, and accumulate substantial amounts of other health beneficial phenolic compounds (i.e., flavonols, hydroxycinnamic acids).
Laurine Garros   +15 more
doaj   +1 more source

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