Results 151 to 160 of about 2,552,257 (360)

How the Removal of Deposit Rate Ceilings Has Changed Monetary Transmission in the US: Theory and Evidence [PDF]

open access: yes
A test for the cointegrating rank of a vector autoregressive (VAR) process with a possible shift and broken linear trend is proposed. The break point is assumed to be known. The setup is a VAR process for cointegrated variables.
Karel Mertens
core  

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Does Foreign Direct Investment Promote Regional Development in Developed Countries? A Markov Chain Approach for US States. [PDF]

open access: yes
Direktinvestition; Regionale Entwicklung; Sozialprodukt; Regionale Disparität; Schätzung; USA;Markov transition probability , likelihood ratio test , FDI , per-capita income , regional development , United States of America;
Bode, Eckhardt, Nunnenkamp, Peter
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Case Study of Binary Hypothesis Test Using ML

open access: yesEngineering Proceedings
Artificial intelligence has attracted much attention due to its learning capability to solve versatile problems. Using a convolutional neural network in machine learning (ML), we investigated the binary hypothesis test, which is a fundamental problem in ...
Shang-Hua Chin, Cheng-Yu Chin
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

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