A likelihood ratio test on temporal trends in age-period-cohort models with applications to the disparities of heart disease mortality among US populations and comparison with Japan. [PDF]
Fu W, Ding J, Gao K, Ma S, Tian L.
europepmc +1 more source
How the Removal of Deposit Rate Ceilings Has Changed Monetary Transmission in the US: Theory and Evidence [PDF]
A test for the cointegrating rank of a vector autoregressive (VAR) process with a possible shift and broken linear trend is proposed. The break point is assumed to be known. The setup is a VAR process for cointegrated variables.
Karel Mertens
core
Strength through diversity: how cancers thrive when clones cooperate
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Does Foreign Direct Investment Promote Regional Development in Developed Countries? A Markov Chain Approach for US States. [PDF]
Direktinvestition; Regionale Entwicklung; Sozialprodukt; Regionale Disparität; Schätzung; USA;Markov transition probability , likelihood ratio test , FDI , per-capita income , regional development , United States of America;
Bode, Eckhardt, Nunnenkamp, Peter
core
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Case Study of Binary Hypothesis Test Using ML
Artificial intelligence has attracted much attention due to its learning capability to solve versatile problems. Using a convolutional neural network in machine learning (ML), we investigated the binary hypothesis test, which is a fundamental problem in ...
Shang-Hua Chin, Cheng-Yu Chin
doaj +1 more source
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
A likelihood ratio test for detecting shifts in homeolog expression ratios in allopolyploids. [PDF]
Sun J, Sese J, Shimizu KK.
europepmc +2 more sources
Stepdown likelihood ratio test on each parameter component in testing equality of covariance matrices [PDF]
Akimichi Takemura
openalex +1 more source

