Results 161 to 170 of about 2,552,257 (360)

Empirical Likelihood Ratio Test for the Epidemic Change Model

open access: diamond, 2021
Wei Ning, Junvie Pailden, Arjun K. Gupta
openalex   +1 more source

Generalized Likelihood Ratio Test for Detection of Gaussian Rank-One Signals in Gaussian Noise With Unknown Statistics

open access: yesIEEE Transactions on Signal Processing, 2017
O. Besson   +4 more
semanticscholar   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

TESTING FOR THE MONOTONE LIKELIHOOD RATIO ASSUMPTION [PDF]

open access: green, 2003
Jutta Roosen   +3 more
openalex   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Estimation and Statistical Test in Bivariate Binary Probit Model

open access: yesJurnal Ilmu Dasar, 2012
One of the models that can be used to analyze two binary response variables data is bivariate binary probit model. This paper tried to estimate the parameters of bivariate binary probit model using Maximum Likelihood Estimationmethod, whereastoget the ...
Vita Ratnasari   +3 more
doaj  

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