Results 211 to 220 of about 2,552,257 (360)

Analysis of survival outcomes using likelihood ratio test in trials incorporating patient's treatment choice. [PDF]

J Appl Stat
Chahine RA, Aban I.
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

A Continuous Extension of Gene Set Enrichment Analysis Using the Likelihood Ratio Test Statistics Identifies Vascular Endothelial Growth Factor as a Candidate Pathway for Alzheimer's Disease via ITGA5. [PDF]

J Alzheimers Dis
Mahzarnia A, Lutz MW, Badea A.
europepmc   +1 more source

The Weighting is the Hardest Part: On the Behavior of the Likelihood Ratio Test and the Score Test Under a Data-Driven Weighting Scheme in Sequenced Samples. [PDF]

Twin Res Hum Genet, 2017
Minică CC, Genovese G, Hultman CM, Pool R, Vink JM, Neale MC, Dolan CV, Neale BM.   +7 more
europepmc   +1 more source

Asymptotic expansion of the null distribution of the likelihood ratio statistic for testing the equality of variances in a nonnormal one-way {ANOVA} model

, 2003
Tetsuji Tonda, Hirofumi Wakaki
openalex   +1 more source

Erratum: The likelihood ratio test under nonstandard conditions: Testing the Markov switching model of GNP

, 1996
B. Hansen
semanticscholar   +1 more source

An improved likelihood ratio test for detecting site-specific functional divergence among clades of protein-coding genes.

Molecular biology and evolution, 2012
Cameron J Weadick, B. Chang
semanticscholar   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Large Deviations of Likelihood Ratio Statistics with Applications to Sequential Testing [PDF]

, 1978
Michael Woodroofe
openalex   +1 more source