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The Likelihood Ratio Test and Full Bayesian Significance Test under small sample sizes for contingency tables

open access: yes, 2017
Hypothesis testing in contingency tables is usually based on asymptotic results, thereby restricting its proper use to large samples. To study these tests in small samples, we consider the likelihood ratio test and define an accurate index, the P-value ...
Diniz, Marcio A.   +3 more
core   +1 more source

Power comparison among tests for fractional unit roots [PDF]

open access: yes, 2008
This article compares the asymptotic power properties of the Wald, the Lagrange Multiplier and the Likelihood Ratio test for fractional unit roots. The paper shows that there is an asymptotic inequality between the three tests that holds under fixed ...
Lobato, Ignacio N., Velasco, Carlos
core   +3 more sources

Survival for Children Diagnosed With Wilms Tumour (2012–2022) Registered in the UK and Ireland Improving Population Outcomes for Renal Tumours of Childhood (IMPORT) Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Improving Population Outcomes for Renal Tumours of childhood (IMPORT) is a prospective clinical observational study capturing detailed demographic and outcome data on children and young people diagnosed with renal tumours in the United Kingdom and the Republic of Ireland.
Naomi Ssenyonga   +56 more
wiley   +1 more source

Searching for new phenomena with profile likelihood ratio tests [PDF]

open access: yesNature Reviews Physics, 2019
Likelihood ratio tests are standard statistical tools used in particle physics to perform tests of hypotheses. The null distribution of the likelihood ratio test statistic is often assumed to be χ2, following Wilks’ theorem.
S. Algeri   +3 more
semanticscholar   +1 more source

Relation of Adverse Childhood Experiences to Clinical and Patient‐Reported Outcomes for Adults With Sickle Cell Disease: A Registry Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adverse childhood experiences (ACEs) are stressful or traumatic events prior to age 18 that are known to have a lasting impact on individuals’ health and well‐being. There is a gap in understanding the relationship between ACEs and Other Life Stressors and health status for adults with sickle cell disease (SCD).
Marsha Treadwell   +8 more
wiley   +1 more source

Detecting level shifts in the presence of conditional heteroscedasticity. [PDF]

open access: yes, 2003
The objective of this paper is to analyze the finite sample performance of two variants of the likelihood ratio test for detecting a level shift in uncorrelated conditionally heteroscedastic time series.
Carnero, María Ángeles   +2 more
core   +2 more sources

What to Do When Medical Evidence Can Only Be Generated Through Routine Data: An Example From Pediatric Oncology

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Children undergoing allogeneic stem cell transplantation often receive off‐label rituximab treatment for Epstein–Barr virus reactivation, using adult dosing without pediatric evidence. This project aims to develop a clinical decision support tool (CDSS) that provides evidence‐based dosing scenarios by analyzing real‐world patient data.
Birgit Burkhardt   +2 more
wiley   +1 more source

Power analysis for RNA-Seq differential expression studies

open access: yesBMC Bioinformatics, 2017
Background Sample size calculation and power estimation are essential components of experimental designs in biomedical research. It is very challenging to estimate power for RNA-Seq differential expression under complex experimental designs.
Lianbo Yu, Soledad Fernandez, Guy Brock
doaj   +1 more source

Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li   +6 more
wiley   +1 more source

Inflated Kumaraswamy distributions

open access: yesAnais da Academia Brasileira de Ciências, 2019
: The Kumaraswamy distribution is useful for modeling variables whose support is the standard unit interval, i.e., (0, 1). It is not uncommon, however, for the data to contain zeros and/or ones.
FRANCISCO CRIBARI-NETO, JÉSSICA SANTOS
doaj   +1 more source

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