Results 121 to 130 of about 13,556,907 (351)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Towards the mother-of-all-models: customised construction of the mark-recapture likelihood function [PDF]

Animal Biodiversity and Conservation, 2004
With a proliferation of mark–recapture models and studies collecting mark–recapture data, software and analysis methods are being continually revised. We consider the construction of the likelihood for a general model that incorporates all the features ...
Barker, R. J., White, G. C.
doaj  

Penalized Composite Likelihood Estimation for Spatial Generalized Linear Mixed Models [PDF]

Journal of Sciences, Islamic Republic of Iran
When discussing non-Gaussian spatially correlated variables, generalized linear mixed models have enough flexibility for modeling various data types. However, the maximum likelihood methods are plagued with substantial calculations for large data sets ...
Mohsen Mohammadzadeh, Leyla Salehi
doaj   +1 more source

Local Likelihood Estimation for Covariance Functions with Spatially-Varying Parameters: The convoSPAT Package for R [PDF]

, 2017
Mark D. Risser, Catherine A. Calder
openalex   +1 more source

Upper and Lower Class Functions for Maximum Likelihood Estimator for\n Single server Queues [PDF]

, 2020
Sarat Kumar Acharya, Saroja Kumar Singh
openalex   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Maximum Likelihood Time Delay Estimation Based on Monte Carlo Importance Sampling in Multipath Environment

International Journal of Antennas and Propagation, 2017
In multipath environment, the computation complexity of single snapshot maximum likelihood for time delay estimation is huge. In particular, the computational complexity of grid search method increases exponentially with the increase of dimension.
Bin Ba, Weijia Cui, Daming Wang, Jianhui Wang   +3 more
doaj   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Parameter Estimation of the Extended Vasiček Model

Walailak Journal of Science and Technology, 2011
In this paper, an estimate of the drift and diffusion parameters of the extended Vasiček model is presented. The estimate is based on the method of maximum likelihood.
Sanae RUJIVAN
doaj   +1 more source

Sparse learning of maximum likelihood model for optimization of complex loss function [PDF]

, 2015
Ning Zhang, Prathamesh Chandrasekar
openalex   +1 more source