Results 101 to 110 of about 19,296,908 (351)
The distribution of calibrated likelihood functions on the probability-likelihood Aitchison simplex
Preprint.
Paul-Gauthier Noé +4 more
openaire +2 more sources
Maximum Likelihood Estimation of Latent Affine Processes [PDF]
This article develops a direct filtration-based maximum likelihood methodology for estimating the parameters and realizations of latent affine processes.
David S. Bates
core
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Lost in the Vaso‐Occlusion: A Patient's Abdominal Pain Returns With a Vengeance
Pediatric Blood &Cancer, EarlyView.
Dunia Hatabah +5 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Using a Neural Network to Approximate the Negative Log Likelihood Function [PDF]
An increasingly frequent challenge faced in HEP data analysis is to characterize the agreement between a prediction that depends on a dozen or more model parameters—such as predictions coming from an effective field theory (EFT) framework—and the ...
Liu Shenghua +6 more
doaj +1 more source
How likelihood and identification went Bayesian [PDF]
This paper considers how the concepts of likelihood and identification became part of Bayesian theory. This makes a nice study in the development of concepts in statistical theory.
Aldrich, John
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The estimation of the uncertainty associated with stage-discharge relations is a challenge to the hydrologists. Bayesian inference with likelihood estimator is a promissory approach.
Maldonado Luiz Henrique +2 more
doaj +1 more source

