Results 121 to 130 of about 19,296,908 (351)

Maximization of the two-parameter multivariate normal likelihood avoiding logarithm and differentiation

open access: yesResearch in Statistics
We consider the classical problem of maximizing the likelihood function of the mean vector and the dispersion matrix given a sample from the family of multivariate Normal distributions.
Suman Majumdar
doaj   +1 more source

FPGA Acceleration of the phylogenetic likelihood function for Bayesian MCMC inference methods

open access: yesBMC Bioinformatics, 2010
Background Likelihood (ML)-based phylogenetic inference has become a popular method for estimating the evolutionary relationships among species based on genomic sequence data.
Bakos Jason D, Zierke Stephanie
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

An unconditional maximum likelihood test for a unit root [PDF]

open access: yes, 1993
We investigate a test for unit roots in autoregressive time series based on maximization of the unconditional likelihood. This is the likelihood function appropriate for stationary time series.
González-Farias, Graciela   +1 more
core   +1 more source

Towards the mother-of-all-models: customised construction of the mark-recapture likelihood function [PDF]

open access: yesAnimal Biodiversity and Conservation, 2004
With a proliferation of mark–recapture models and studies collecting mark–recapture data, software and analysis methods are being continually revised. We consider the construction of the likelihood for a general model that incorporates all the features ...
Barker, R. J., White, G. C.
doaj  

Efficient Likelihood Evaluation of State-Space Representations [PDF]

open access: yes
We develop a numerical procedure that facilitates efficient likelihood evaluation in applications involving non-linear and non-Gaussian state-space models.
David N. DeJong   +4 more
core  

Restricted Maximum Likelihood Estimation of Variance Components for Univariate Animal Models Using Sparse Matrix Techniques and Average Information [PDF]

open access: yes, 1995
An algorithm is described to estimate variance components for a univariate animal model using REML. Sparse matrix techniques are employed to calculate those elements of the inverse of the coefficient matrix required for the first derivatives of the ...
JOHNSON, DL, THOMPSON, R
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Using the Genetic Algorithm to Maximize the Likelihood Function of Normal Distribution [PDF]

open access: yesالمجلة العراقية للعلوم الاحصائية, 2008
In this research, the genetic algorithm (GA) has been carried out. This application is considered to be a manufacturing treatment to find the value which maximizes the likelihood function . An algorithm has been proposed to find the values which maximize.
doaj   +1 more source

"Empirical Likelihood-Based Inference in Conditional Moment Restriction Models" [PDF]

open access: yes
This paper proposes an asymptotically efficient method for estimating models with conditional moment restrictions. Our estimator generalizes the maximum empirical likelihood estimator (MELE) of Qin and Lawless (1994).
Hyungtaik Ahn   +2 more
core  

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