A Bartlett-type correction for likelihood ratio tests with application to testing equality of Gaussian graphical models. [PDF]
Banzato E +3 more
europepmc +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Detection for physical-layer network coding in two-way relay channels
The detection for physical-layer network coding (PNC) in two-way relay channels was investigated.Maximum-likelihood (ML) detection not only had great performance but also had high computational complexity.Therefore,without channel state information (CSI)
Wei YAN, Yue-ming CAI, Cheng-kang PAN
doaj
A likelihood ratio approach for utilizing case-control data in the clinical classification of rare sequence variants: application to <i>BRCA1</i> and <i>BRCA2</i>. [PDF]
Zanti M +125 more
europepmc +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Letter to Editor: Interpretation and Application of the Likelihood Ratio to Clinical Practice in Thoracic Oncology. [PDF]
Springmeyer S, Jett J.
europepmc +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
A score based likelihood ratio framework for deepfake image identification in forensic science. [PDF]
Guo T, Li J, Tang Y.
europepmc +1 more source
A likelihood ratio test for the homogeneity of between-study variance in network meta-analysis. [PDF]
Hu D, Wang C, O'Connor AM.
europepmc +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source

