Results 131 to 140 of about 4,069,627 (285)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Prueba de homogeneidad de la dispersión para datos de proporción sobredispersos mediante regresión beta

open access: yesRevista Integración, 2014
En este artículo se propone un procedimiento para verificar la hipótesis de homogeneidad del parámetro de dispersión usando regresión beta, cuando se tienen datos de proporción sobredispersos.
Mario Morales, Jose Lozano
doaj  

Comparison between the Conditional Likelihood Ratio and the Usual Likelihood Ratio Tests

open access: yesJournal of the Royal Statistical Society Series B: Statistical Methodology, 1992
SUMMARY This paper compares, under contiguous alternatives, the conditional likelihood ratio test of Cox and Reid with the usual likelihood ratio test on the basis of second-order power. It is seen that although the power of the former is identical, up to the second order, with that of the likelihood ratio test with known nuisance ...
openaire   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Empirical likelihood estimators for the error distribution in nonparametric regression models [PDF]

open access: yes
The aim of this paper is to show that existing estimators for the error distribution in nonparametric regression models can be improved when additional information about the distribution is included by the empirical likelihood method.
Kiwitt, Sebastian   +2 more
core  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

The impact of commercialisation on the evaluation of DNA evidence

open access: yesFrontiers in Genetics, 2013
Graham eJackson, Graham eJackson
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Understanding likelihood ratios

open access: yesCurrent Medicine Research and Practice, 2012
The utility of a diagnostic test is expressed in various statistical terms such as sensitivity, specificity, positive predictive value, negative predictive value and so on.
Sourabh Singh   +3 more
doaj  

Computer assisted diagnosis of Alzheimer's disease using statistical likelihood-ratio test. [PDF]

open access: yesPLoS One, 2023
Zheng X   +4 more
europepmc   +1 more source

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