Results 131 to 140 of about 813,652 (289)

Prueba de homogeneidad de la dispersión para datos de proporción sobredispersos mediante regresión beta

open access: yesRevista Integración, 2014
En este artículo se propone un procedimiento para verificar la hipótesis de homogeneidad del parámetro de dispersión usando regresión beta, cuando se tienen datos de proporción sobredispersos.
Mario Morales, Jose Lozano
doaj  

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Lack-of-fit tests in semiparametric mixed models. [PDF]

open access: yes
In this paper we obtain the asymptotic distribution of restricted likelihood ratio tests in mixed linear models with a fixed and finite number of random effects.
Claeskens, Gerda   +2 more
core  

Assessment of Body Mass Index for Obesity Diagnosis in the Mexican Population: A Cross-Sectional Analysis

open access: yesObesities
The diagnosis of obesity is conventionally determined by the Body Mass Index (BMI), with a threshold of 30 being extensively accepted. However, the validity of this cutoff point is subject to variation due to ethnic differences, and its accuracy in the ...
Jorge Alejandro Ayala San Pedro   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Testing for Non-nested Conditional Moment Retrictions via Conditional Empirical Likelihood [PDF]

open access: yes
We propose non-nested tests for competing conditional moment resctriction models using a method of empirical likelihood. Our tests are based on the method of conditional empirical likelihood developed by Kitamura, Tripathi and Ahn (2004) and Zhang and ...
Taisuke Otsu, Yoon-Jae Whang
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

EMPIRICAL LIKELIHOOD ESTIMATORS OF THE LINEAR SIMULTANEOUS EQUATIONS MODEL

open access: yes
Information theoretic estimators are specified for a system of linear simultaneous equations, including maximum empirical likelihood, maximum empirical exponential likelihood, and maximum log Euclidean likelihood.
Judge, George G.   +2 more
core  

The impact of commercialisation on the evaluation of DNA evidence

open access: yesFrontiers in Genetics, 2013
Graham eJackson, Graham eJackson
doaj   +1 more source

Understanding likelihood ratios

open access: yesCurrent Medicine Research and Practice, 2012
The utility of a diagnostic test is expressed in various statistical terms such as sensitivity, specificity, positive predictive value, negative predictive value and so on.
Sourabh Singh   +3 more
doaj  

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