Results 161 to 170 of about 4,069,627 (285)

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

A score based likelihood ratio framework for deepfake image identification in forensic science. [PDF]

Sci Rep
Guo T, Li J, Tang Y.
europepmc   +1 more source

A Bartlett-type correction for likelihood ratio tests with application to testing equality of Gaussian graphical models. [PDF]

Stat Probab Lett, 2023
Banzato E, Chiogna M, Djordjilović V, Risso D.   +3 more
europepmc   +1 more source

Semiparametric Regression Analysis under Imputation for Missing Response Data [PDF]

We develop inference tools in a semiparametric regression model with missing response data. A semiparametric regression imputation estimator, a marginal average estimator and a (marginal) propensity score weighted estimator are defined.
Qihua Wang, Wolfgang Haerdle, Oliver Linton   +2 more
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Commentary: Likelihood Ratio as Weight of Forensic Evidence: A Closer Look

Frontiers in Genetics, 2018
Colin Aitken, Anders Nordgaard, Franco Taroni, Alex Biedermann   +3 more
doaj   +1 more source

Common TF-IDF variants arise as key components in the test statistic of a penalized likelihood-ratio test for word burstiness. [PDF]

Discov Comput
Ahmed Z, Sheridan P, McIsaac M, Farooque AA.   +3 more
europepmc   +1 more source

Optimized serum ferritin prediction of iron overload in transfusion-dependent thalassemia: likelihood ratio and age-adjustment approach. [PDF]

Ann Saudi Med, 2023
Kurban LA, Almarri BK, Alshamsi MH, Abdelrahman SS, Alwahshi SG, Alhorani Q, Syed R, Bakoush O.   +7 more
europepmc   +1 more source

A Two-Sample Non-Parametric Likelihood Ratio Test [PDF]

This paper proposes a test for the hypothesis that two samples have the same distribution. The likelihood ratio test of Portnoy (1988) is applied in the context of the consistent series density estimator of Crain (1974) and Barron and Sheu (1991).
Patrick Marsh
core  

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source