Results 41 to 50 of about 813,652 (289)

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi   +5 more
wiley   +1 more source

The Use of Probabilistic and Statistical Methods to Test the Significance of Scientific Evidence: Comparative Analysis of Current Forensic Practices in Russia and Abroad

open access: yesТеория и практика судебной экспертизы, 2018
The article addresses the problem of developing scientifically sound approaches and quantitative criteria for assessing reliability of expert evidence that take into account the contextual information contained in case materials and are based on ...
A. I. Usov   +2 more
doaj   +1 more source

Different diagnostic strategies for different settings

open access: yesGeriatric Care, 2021
Diagnostic strategies should always take into consideration the setting in which they are administered. The predictive value, positive or negative of a clinical sign or diagnostic test has a different weight in family medicine than in the hospital ...
Ferdinando Petrazzuoli
doaj   +1 more source

On the Distribution of the Likelihood Ratio

open access: yesThe Annals of Mathematical Statistics, 1956
In an investigation of the distribution of the likelihood ratio $\lambda$, Wilks [3] proved, under certain regularity conditions, that $-2 \ln \lambda$ is, except for terms of order $1/\sqrt n$, distributed like $\chi^2$ with $k - m$ degrees of freedom, where $k$ is the dimension of the parameter space $\Omega$ of admissible hypotheses and $m$ is the ...
openaire   +2 more sources

Dietary Protein Intake and Peritoneal Protein Losses in Peritoneal Dialysis Patients

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) patients lose protein in their waste dialysate, potentially increasing their risk for malnutrition. We wished to determine whether there was any association between losses and dietary protein intake (DPI). Methods DPI was assessed from 24‐h dietary recall using Nutrics software.
Haalah Shaaker, Andrew Davenport
wiley   +1 more source

Evidence Based Medicine; Positive and Negative Likelihood Ratios of Diagnostic Tests

open access: yesطب اورژانس ایران, 2015
In the previous two parts of educational manuscript series in Emergency, we explained some screening characteristics of diagnostic tests including accuracy, sensitivity, specificity, and positive and negative predictive values.
Alireza Baratloo, Saeed Safari
doaj  

Differential diagnostic utilities of combined testing for islet cell antibody, glutamic acid decarboxylase antibody, and tyrosine phosphatase antibody

open access: yesСахарный диабет, 2018
Background. Beta-cell antibody tests are used for the differential diagnosis of diabetes mellitus. They permit to discriminate between the type 1 diabetes (T1D) and non-autoimmune diabetes types.
Alexei V. Timofeev   +10 more
doaj   +1 more source

On the Distribution of the Likelihood Ratio

open access: yesThe Annals of Mathematical Statistics, 1954
A classical result due to Wilks [1] on the distribution of the likelihood ratio $\lambda$ is the following. Under suitable regularity conditions, if the hypothesis that a parameter $\theta$ lies on an $r$-dimensional hyperplane of $k$-dimensional space is true, the distribution of $-2 \log \lambda$ is asymptotically that of $\chi^2$ with $k - r ...
openaire   +3 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Consistency and asymptotic normality of the maximum likelihood estimator in a zero-inflated generalized Poisson regression [PDF]

open access: yes, 2005
Poisson regression models for count variables have been utilized in many applications. However, in many problems overdispersion and zero-inflation occur.
Min, Aleksey, Czado, Claudia
core   +1 more source

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