Results 61 to 70 of about 1,980,844 (280)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Concentration Inequalities from Likelihood Ratio Method [PDF]

open access: yes, 2014
We explore the applications of our previously established likelihood-ratio method for deriving concentration inequalities for a wide variety of univariate and multivariate distributions.
Chen, Xinjia
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

INVESTIGATING POPULATION BALANCE IN THE STATE OF GEORGIA USING SPATIAL CLUSTERING [PDF]

open access: yesریاضی و جامعه
Identification of population ratio disruption in the population structure is one of the challenges that every country faces. Population aging is a kind of demographic abnormality that lack of attention causes population problems.
Ali Abolhassani, Somayyeh Tari
doaj   +1 more source

Approximating Likelihood Ratios with Calibrated Discriminative Classifiers [PDF]

open access: yes, 2015
In many fields of science, generalized likelihood ratio tests are established tools for statistical inference. At the same time, it has become increasingly common that a simulator (or generative model) is used to describe complex processes that tie ...
Cranmer, Kyle   +2 more
core   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Specificity of characteristic marks on cartridge cases from 3070 consecutive firings of a Chinese Norinco QSZ-92 9 mm Pistol

open access: yesJournal of Forensic Science and Medicine, 2019
The specificity of marks was evaluated by differences between marks left by the same firearm (within variability) and differences between marks left by different firearms (between variability). The within variability and between variability of firing pin
Feng Dong   +4 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Analysis of Technical Efficiency of Smallholder Cocoa Farmers in Cross River State, Nigeria [PDF]

open access: yesInternational Journal of Agricultural Management and Development, 2012
The technical efficiency involved in cocoa production inCross River State was estimated using the stochastic frontierproduction function analysis. The effects of some selected socio-economic characteristics of the farmers on the efficiencyindices were ...
Agom, Damian Ila   +3 more
doaj  

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