Results 81 to 90 of about 4,069,627 (285)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Empirical likelihood confidence intervals for complex sampling designs
, 2016 We define an empirical likelihood approach which gives consistent design-based confidence intervals which can be calculated without the need of variance estimates, design effects, resampling, joint inclusion probabilities and linearization, even when the
De La Riva Torres, O., Berger, Y.G.
core +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Likelihood Ratio-Based Detection of Facial Features [PDF]
, 2003 One of the first steps in face recognition, after image acquisition, is registration. A simple but effective technique of registration is to align facial features, such as eyes, nose and mouth, as well as possible to a standard face.
Bazen, A.M. +2 more
core +2 more sources
Empirical likelihood inference for the Rao-Hartley-Cochran sampling design
, 2016 The Hartley-Rao-Cochran sampling design is an unequal probability sampling design which can be used to select samples from finite populations. We propose to adjust the empirical likelihood approach for the Hartley-Rao-Cochran sampling design.
Yves G. Berger, Berger, Yves G.
core +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Journal of the Royal Statistical Society Series B: Statistical Methodology, 1992 SUMMARY This paper characterizes priors under which the Bayesian and frequentist Bartlett corrections for the likelihood ratio and the conditional likelihood ratio (CLR) statistics differ by o(1). It is seen that, except for sample points with negligible probability, the CLR statistic has a posterior distribution for which a posterior ...
Ghosh, J. K., Mukerjee, Rahul
openaire +2 more sources
Simulating properties of the likelihood ratio test for a unit root in an explosive second order autoregression [PDF]
This paper provides a means of accurately simulating explosive autoregressive processes, and uses this method to analyse the distribution of the likelihood ratio test statistic for an explosive second order autoregressive process.
Bent Nielsen, J. James Reade
core
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source