Results 61 to 70 of about 12,417,714 (259)

On multipolar magnetic anomaly detection: multipolar signal subspaces, an analytical orthonormal basis, multipolar truncation and detection performance

EURASIP Journal on Advances in Signal Processing
In this paper, we consider the magnetic anomaly detection problem which aims to find ferromagnetic masses by estimating the weak perturbation they induce on local Earth’s magnetic field.
Clément Chenevas-Paule, Steeve Zozor, Laure-Line Rouve, Olivier J. J. Michel, Olivier Pinaud, Romain Kukla   +5 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Testing for the Monotone Likelihood Ratio Assumption [PDF]

Monotonicity of the likelihood ratio for conditioned densities is a common technical assumption in economic models. But we have found no empirical tests for its plausibility.
Hennessy, David A., Roosen, Jutta
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Simulating properties of the likelihood ratio test for a unit root in an explosive second order autoregression [PDF]

This paper provides a means of accurately simulating explosive autoregressive processes, and uses this method to analyse the distribution of the likelihood ratio test statistic for an explosive second order autoregressive process.
Bent Nielsen, J. James Reade
core  

Likelihood-ratio tests and information criteria for the Post Traumatic Growth (PTG) models.

, 2021
Likelihood-ratio tests and information criteria for the Post Traumatic Growth (PTG) models.
Pascal Delamillieure (11840961), Mateusz Zatorski (10654839), Reham Hakem (11840934), Júlia Halamová (7333202), Nuno Ferreira (3504785), Gonzalo Brito-Pons (11840910), Margarita G. Márquez (11840904), Tomasz Komendziński (11840973), Lorena Llobenes (11840922), Catherine Bortolon (7617431), James Kirby (310790), Martin Kanovský (7333205), Kenichi Asano (169804), Shuge Zhang (11840976), Gregoris Simos (11840949), Mariusz Zieba (11840970), Simone Cheli (11840943), Allison C. Kelly (11840958), Paola Lucena-Santos (11840913), Ask Elklit (3475784), Marine Paucsik (11840964), Natali Gumiy (11840925), Noor Habib (11840931), Paul Gilbert (90408), Mariana Linharelhos (11840898), Maria Ileana Costa (11840928), Julia E. Wahl (11840967), Erika Leonardo de Souza (11840919), Jaskaran Basran (7677641), Ahmad Alzahrani (11840940), Daniel Rijo (8700111), Stanley R. Steindl (10337551), Hussain Khrad (11840937), Margareth da Silva Oliveira (11840916), Antonios Kagialis (11051362), Philia Issari (11818592), Sara P. Vilas (11840901), Nicola Petrocchi (9971198), Marcela Matos (3687577), Sónia Gregório (11840907), Vibeke Lunding-Gregersen (11840952), Russell Kolts (11840955), Kirsten McEwan (524718), Elli Tholouli (11840946)   +43 more
core   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

A new class of Lindley distribution: System reliability, simulation and applications

Heliyon
This paper presents a new probability distribution called the DUS Lindley distribution, created by applying the DUS transformation to the traditional Lindley distribution.
Danish Qayoom, Aafaq A. Rather, Najwan Alsadat, Eslam Hussam, Ahmed M. Gemeay   +4 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source