Results 81 to 90 of about 12,417,714 (259)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Generalized empirical likelihood estimators and tests under partial, weak and strong identification [PDF]

open access: yes
The principal purpose of this paper is to describe the performance of generalized empirical likelihood (GEL) methods for time series instrumental variable models specified by nonlinear moment restrictions when identification may be weak.
Patrik Buggenberger, Richard Smith
core  

Omnibus Change Detection in Block Diagonal Covariance Matrix PolSAR Data Illustrated With Simulated and Sentinel-1 Data

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
This article describes the latest developments in our work on complex Wishart distribution-based detection of change in time series of multilook polarimetric synthetic aperture radar data in the covariance matrix representation.
Knut Conradsen   +2 more
doaj   +1 more source

Audio Hiding based on Wavelet Transform and Linear Predictive Coding

open access: yesIraqi Journal for Computers and Informatics, 2016
In this work an efficient method for hiding a speech in audio is proposed. The features of secret speech is extracted with LPC (Linear Predictive Coding), and these parameters embedded in audio in chaotic order.
Jamal Hasoon, Saad Al-Saad
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Quasi Empirical Likelihood Estimation of Moment Condition Models [PDF]

open access: yes
In this paper, I develop a quasi empirical likelihood estimator that has good finite-sample properties when there are many moment conditions. I show that the quasi empirical likelihood estimator, which uses semiparametric efficient estimation, is an ...
Shane M. Sherlund
core  

Diagnostic value of RAS mutations in Bethesda category IV thyroid nodules: a systematic review and meta-analysis

open access: yesFrontiers in Oncology
ObjectivesThyroid nodules classified as Bethesda category IV cannot be diagnosed with fine-needle aspiration. RAS mutations have been linked to thyroid cancer, although it is still unclear if they are useful as a pre-operative molecular screening for ...
Jiayue Sun   +4 more
doaj   +1 more source

The consumption of wine: a analysis of market conducted in Sicily [PDF]

open access: yesRevista Română de Statistică, 2013
The methodology used in conducting the research project was of a quantitative and random kind. Random surveying refers to the identification of the prominent factors, from which consumers’ purchasing behavior derives. In order to carry out the research a
Maurizio Lanfranchi, Carlo Giannetto
doaj  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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