Results 11 to 20 of about 49,716 (300)
ChEMBL-Likeness Score and Database GDBChEMBL [PDF]
Frontiers in Chemistry, 2020 The generated database GDB17 enumerates 166.4 billion molecules up to 17 atoms of C, N, O, S and halogens following simple rules of chemical stability and synthetic feasibility.
Sven Bühlmann, Jean-Louis Reymond
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Natural product-likeness score revisited: an open-source, open-data implementation [PDF]
BMC Bioinformatics, 2012 Background Natural product-likeness of a molecule, i.e. similarity of this molecule to the structure space covered by natural products, is a useful criterion in screening compound libraries and in designing new lead compounds.
Jayaseelan Kalai Vanii +4 more
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, 2023 Recent studies suggest RNAs act as promising drug targets. However, limited development has been achieved in detecting RNA–ligand interactions.
Huiying Zhao (138755) +4 more
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In Silico Resources of Drug-Likeness as a Mirror: What Are We Lacking in Pesticide-Likeness?
, 2021 Unfavorable bioavailability is an important aspect underlying the failure of drug candidates. Computational approaches for evaluating drug-likeness can minimize these risks.
Ge-fei Hao (11426377) +11 more
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Drug Likeness Screening of Black Soybean Flavonoids
, 2023 Screening of drug-likeness and toxicity of compounds contained in black soybeans. A) Screening for drug-likeness, B) Toxicity screening, C) 2D structure of compounds that pass the screening.
Ricadonna Raissa (12081878) +1 more
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Canadian Medical Association Journal, 2019 In their Practice article in CMAJ ,[1][1] Moayedi and colleagues illustrate how challenging it can be to rule in or out acute heart failure in a patient with undifferentiated dyspnea. The authors suggested testing brain natriuretic peptide (BNP) or N-terminal pro BNP (NT-proBNP) level, listing ...
openaire +2 more sources
The inversion effect on the cubic humanness-uncanniness relation in humanlike agents
Frontiers in Psychology, 2023 The uncanny valley describes the typically nonlinear relation between the esthetic appeal of artificial entities and their human likeness. The effect has been attributed to specialized (configural) processing that increases sensitivity to deviations from
Alexander Diel +4 more
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Prediction of Drug-likeness of Central Nervous System Drug Candidates Using a Feed-Forward Neural Network Based on Chemical Structure [PDF]
, 2020 Modern medical science has been greatly advanced by the development of new drugs, despite the fact that the process of developing new drugs is costly and time-consuming.
Xiao, Wang, Yi-Gao, Yuan
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Resemblance, Representation and Scepticism: The Metaphysical Role of Berkeley’s Likeness Principle
Journal of Modern Philosophy, 2022 Berkeley’s likeness principle states that only an idea can be like an idea. In this paper, I argue that the principle should be read as a premise only in a metaphysical argument showing that matter cannot instantiate anything like the sensory properties ...
David Bartha
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Drug likeness and medicinal chemistry predictions.
, 2023 Drug likeness and medicinal chemistry predictions.
Marcus Tullius Scotti (7483265) +6 more
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