Results 11 to 20 of about 38,309 (309)

ChEMBL-Likeness Score and Database GDBChEMBL [PDF]

open access: yesFrontiers in Chemistry, 2020
The generated database GDB17 enumerates 166.4 billion molecules up to 17 atoms of C, N, O, S and halogens following simple rules of chemical stability and synthetic feasibility.
Sven Bühlmann, Jean-Louis Reymond
doaj   +2 more sources

Drug repositioning for enzyme modulator based on human metabolite-likeness

open access: yesBMC Bioinformatics, 2017
Background Recently, the metabolite-likeness of the drug space has emerged and has opened a new possibility for exploring human metabolite-like candidates in drug discovery.
Yoon Hyeok Lee   +4 more
doaj   +2 more sources

Improving the Human-Likeness of Game AI’s Moves by Combining Multiple Prediction Models [PDF]

open access: yes, 2023
Strong game AI’s moves are sometimes strange or difficult for humans to understand. To achieve better human-computer interaction, researchers try to create human-like game AI.
Ogawa, Tatsuyoshi   +2 more
core   +1 more source

Characterizing RNA-binding ligands on structures, chemical information, binding affinity and drug-likeness

open access: yes, 2023
Recent studies suggest RNAs act as promising drug targets. However, limited development has been achieved in detecting RNA–ligand interactions.
Huiying Zhao (138755)   +4 more
core   +1 more source

In Silico Resources of Drug-Likeness as a Mirror: What Are We Lacking in Pesticide-Likeness?

open access: yes, 2021
Unfavorable bioavailability is an important aspect underlying the failure of drug candidates. Computational approaches for evaluating drug-likeness can minimize these risks.
Ge-fei Hao (11426377)   +11 more
core   +1 more source

Association Between Self-Perceived General Human-Likeness During Walking and Walking Speed in Stroke Patients: A Preliminary Study

open access: yesRehabilitation Process and Outcome, 2022
The difference between the walking speeds of stroke patients and the general population may influence the self-perception of patients, who perceive their walk as lacking general human-likeness.
Kazuki Hayashida   +5 more
doaj   +1 more source

The inversion effect on the cubic humanness-uncanniness relation in humanlike agents

open access: yesFrontiers in Psychology, 2023
The uncanny valley describes the typically nonlinear relation between the esthetic appeal of artificial entities and their human likeness. The effect has been attributed to specialized (configural) processing that increases sensitivity to deviations from
Alexander Diel   +4 more
doaj   +1 more source

How likely is “likely”? [PDF]

open access: yesCanadian Medical Association Journal, 2019
In their Practice article in CMAJ ,[1][1] Moayedi and colleagues illustrate how challenging it can be to rule in or out acute heart failure in a patient with undifferentiated dyspnea. The authors suggested testing brain natriuretic peptide (BNP) or N-terminal pro BNP (NT-proBNP) level, listing ...
openaire   +2 more sources

Resemblance, Representation and Scepticism: The Metaphysical Role of Berkeley’s Likeness Principle

open access: yesJournal of Modern Philosophy, 2022
Berkeley’s likeness principle states that only an idea can be like an idea. In this paper, I argue that the principle should be read as a premise only in a metaphysical argument showing that matter cannot instantiate anything like the sensory properties ...
David Bartha
doaj   +4 more sources

Percival Everett by Virgil Russell : le laboratoire du roman

open access: yesMiranda: Revue Pluridisciplinaire du Monde Anglophone, 2018
In his highly metanarrative novel, Percival Everett by Virgil Russell, Percival Everett delves into the making of fiction, not so much showing what happens behind the scene as exhibiting a text that is no longer clearly distinct from the work that made ...
Anne-Laure Tissut
doaj   +1 more source

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