Results 91 to 100 of about 24,999 (309)

Study of risk factors affecting the limb salvage in patients with lower extremity arterial trauma

open access: yesIndian Journal of Vascular and Endovascular Surgery, 2019
Background: Vascular injury in extremity is a complication of both blunt and penetrating trauma. In Indian scenario, patients generally present late to the tertiary care center with mangled extremity for treatment.
Mukesh Kumar Garg   +5 more
doaj   +1 more source

Mechanical Activation of Piezo1 Drives Osteoarthritis Through Kdm5c‐Mediated Epigenetic Silencing

open access: yesAdvanced Science, EarlyView.
Excessive mechanical stress activates Piezo1, triggering Ca2+‐dependent cytoskeletal forces that deform the nucleus and reduce H3K4me3. Kdm5c demethylates H3K4me3 at Col2a1 and Runx3 promoters. Kdm5c knockout rescues degradation. Repurposed telmisartan directly inhibits Kdm5c, blocking this axis and showing disease‐modifying efficacy in mouse OA models
Tianyou Kan   +13 more
wiley   +1 more source

Soft Tissue Sarcoma of Lower Extremities Treated by Limb Salvage Surgery and Adjuvant Radiotherapy; Case Series [PDF]

open access: yesAin-Shams Journal of Surgery
Introduction: Soft Tissue Sarcoma (STS) is a rare type of cancer with a dismal prognosis. Early diagnosis has animpact on the outcome of the treatment of soft tissue sarcoma.
Ayman Elnemr   +3 more
doaj   +1 more source

Criteria and outcome of limb salvage surgery. [PDF]

open access: yes, 2011
When sufficient margins of resection surrounding the tumor can be achieved, limb salvage surgery, as opposed to amputation, has become the standard of care in treating patients with bone and soft tissue sarcoma of the extremities.
Coll Mesa L   +5 more
core  

Limb Salvage Does Not Predict Functional Limb Outcome after Revascularization for Traumatic Acute Limb Ischemia [PDF]

open access: yes, 2020
BackgroundTraumatic vascular injury leading to acute limb ischemia (ALI) is an uncommon problem with a potential for high morbidity. We describe a contemporary series of patients with traumatic ALI managed primarily by vascular surgeons at a tertiary ...
Dasari, Mohini   +7 more
core   +1 more source

AI‐Assisted IoT‐Enabled ECG Monitoring: Integrating Foundational and Generative AI Tools for Sustainable Smart Healthcare—Recent Trends

open access: yesAI &Innovation, EarlyView.
ABSTRACT The rapid evolution of the Internet of Things (IoT) has significantly advanced the field of electrocardiogram (ECG) monitoring, enabling real‐time, remote, and patient‐centric cardiac care. This paper presents a comprehensive survey of AI assisted IoT‐based ECG monitoring systems, focusing on the integration of emerging technologies such as ...
Amrita Choudhury   +2 more
wiley   +1 more source

Multiple limb salvage attempts for diabetic foot infections [PDF]

open access: yes, 2017
Aims Limb salvage for diabetic foot infections often require multiple procedures. Some patients will eventually end up with below knee amputation (BKA) when all limb salvage attempts fail.
A. Nather   +3 more
core   +1 more source

A case of budding speciation in the California Floristic Province and infraspecific divergence in Abronia villosa

open access: yesAmerican Journal of Botany, EarlyView.
Abstract Premise Budding speciation occurs when peripheral populations adapt to local ecological conditions and “bud” off from a widespread progenitor species. Traditionally regarded as rare because of its sympatric and parapatric nature, budding speciation is largely understudied.
Eli J. Allen   +3 more
wiley   +1 more source

How do Australian podiatrists manage patients with diabetes? The Australian diabetic foot management survey

open access: yesJournal of Foot and Ankle Research, 2015
Background Diabetic foot complications are the leading cause of lower extremity amputation and diabetes‐related hospitalisation in Australia. Studies demonstrate significant reductions in amputations and hospitalisation when health professionals ...
Thomas R Quinton   +4 more
doaj   +1 more source

Autotransfusion with recovery of blood loss in conservative surgery of the lower limb [PDF]

open access: yes, 1988
Autotransfusion with recovery of blood loss in conservative surgery of the lower ...
CAMPANACCI M.   +3 more
core  

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