Results 71 to 80 of about 106,775 (387)

Long-term complications of continent catheterizable channels: a problem for transitional urologists. [PDF]

open access: yes, 2018
A majority of the transitional urology patient population have neurogenic bladder and many of these patients have undergone creation of continent catheterizable channels (CCCs) to facilitate bladder emptying.
Baradaran, Nima   +2 more
core  

Inverted 'V' osteotomy excision arthroplasty for bony ankylosed elbows [PDF]

open access: yes, 2011
Background Bony ankylosis of elbow is challenging and difficult problem to treat. The options are excision arthroplasty and total elbow replacement.
Chadrabose Rex   +5 more
core   +2 more sources

Targeted H2S Delivery System Attenuates Blood‐Spinal Cord Barrier Disruption after Spinal Cord Injury by Reshaping the Ferritinophagy Pathway

open access: yesAdvanced Science, EarlyView.
The αvβ3‐mediated SPRC@MPDA‐RGD targets broken endothelial cells and controllably releases SPRC. CSE is then activated to produce endogenous H2S, which inhibits ferritinophagy. In brief, H2S inhibits autophagy by activating the PI3K/Akt/mTOR pathway, thereby suppressing the ferroptosis process mediated by NCOA4, and ultimately promoting the ...
Zhiheng Chen   +11 more
wiley   +1 more source

A Photothermal Transducer Regulates Transmembrane Calcium Flow for Synergistic Osteoarthritis Therapy

open access: yesAdvanced Science, EarlyView.
Upon NIR irradiation at 808 nm, the activity of TRPV4 was inhibited by M2M@BPSC, which led to reduced calcium influx, mitochondrial protection, and, importantly, the transcriptional activation of the STAT6‐EGR2 pathway. The improved macrophage function indirectly readjusts the equilibrium between C‐ECM and F‐ECM to reconstruct a suitable ...
Chenqi Yu   +11 more
wiley   +1 more source

Innovation in proximal femoral replacement for oncology patients—A novel eggshell procedure

open access: yesJournal of Bone Oncology, 2023
Purpose: Proximal femoral replacement (PFR) for oncology patients is gaining interest as a limb salvage operation due to its obvious advantages.
Jiazheng Zhao, Xiaowei Ma, Helin Feng
doaj   +1 more source

FASLG Derived from Fibroblasts in Hydroxyapatite‐Rich Microenvironment Induces Urothelial Anoikis to Trigger Randall's Plaque Exposure

open access: yesAdvanced Science, EarlyView.
Randall's plaques (RP) serve as the nidus for calcium oxalate (CaOx) kidney stones. The current study reveals that hydroxyapatite (HAP) crystals activate the THY1–GSK3α/β–β‐catenin axis in renal interstitial fibroblasts (hRIFs), inducing FASLG secretion.
Minghui Liu   +14 more
wiley   +1 more source

Mechanically Robust Biodegradable Stents With Theragenerative Vascular Responses via Combined 3D Printing and Janus Nanoengineering

open access: yesAdvanced Science, EarlyView.
This work introduces a theragenerative 3D‐printed biodegradable stent with Janus nanoarchitecture for spatially controlled vascular healing. A luminal tantalum ion–implanted surface accelerates endothelialization and hemocompatibility, while an abluminal sirolimus/poly‐L‐lactic acid–tantalum layer provides sustained drug release and suppresses smooth ...
Jong Hwa Seo   +19 more
wiley   +1 more source

Terrestrial Cyborg Insects for Real‐Life Applications

open access: yesAdvanced Intelligent Systems, EarlyView.
This article reviews the development of terrestrial cyborg insects from their emergence in 1997 to mid‐2025, examining three key aspects: locomotion control methods, associated challenges with proposed solutions, and practical applications. Framing these biohybrid systems as insect‐scale mobile robots, the review provides foundational insights for new ...
Hai Nhan Le   +10 more
wiley   +1 more source

Limb-salvage surgery offers better five-year survival rate than amputation in patients with limb osteosarcoma treated with neoadjuvant chemotherapy. A systematic review and meta-analysis

open access: yesJournal of Bone Oncology, 2020
Highlights • Osteosarcoma is the most common primary bone sarcoma.• Neoadjuvant chemotherapy combined with limb salvage surgery (LSS) or amputation are the main strategies in treating limb osteosarcoma.• LSS is associated with a higher 5-year overall ...
E. Papakonstantinou   +6 more
semanticscholar   +1 more source

Three-dimension-printed custom-made prosthetic reconstructions: from revision surgery to oncologic reconstructions [PDF]

open access: yes, 2019
Background The use of custom-made 3D-printed prostheses for reconstruction of severe bone defects in selected cases is increasing. The aims of this study were to evaluate (1) the feasibility of surgical reconstruction with these prostheses in oncologic ...
Angelini, Andrea   +5 more
core   +1 more source

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