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Limbic encephalitis – a review
The clinical features of limbic encephalitis are diverse and early diagnosis of the disorder is frequently difficult. Four patients with limbic encephalitis are described. An antineuronal antibody was identified in three of these patients. Antibodies directed against voltage-gated potassium channels, the N-methyl-D-aspartate receptor and an ...
N E Anderson, N E Anderson
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Limbic encephalitis (LE) is a clinical syndrome defined by subacutely evolving limbic signs and symptoms with structural and functional evidence of mediotemporal damage in the absence of a better explanation than an autoimmune (or paraneoplastic) cause. There are features common to all forms of LE.
Bien, Christian, Christian G. Bien
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Limbic encephalitis and psychosis
General Hospital Psychiatry, 2013To report a case of limbic encephalitis (LE) presenting with psychosis.Case report.A woman with LE initially presented with acute psychotic symptoms. Magnetic resonance imaging (MRI) showed hyperintensity in bilateral temporal lobes. Paraneoplastic and autoimmune antibodies were negative, but symptoms resolved after starting methylprednisolone.A ...
Kairav, Shah +5 more
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The diagnosis and treatment of limbic encephalitis
Acta Neurologica Scandinavica, 2012The term limbic encephalitis (LE) was first introduced in 1968. While this disease was initially considered rare and is often fatal with very few treatment options, several reports published in the last decade provide a better description of this condition as well as possible causes and some cases of successful treatment.
F, Asztely, E, Kumlien
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Limbic encephalitis: two cases
Journal of Neuroimmunology, 1988L Hermle, B Volk, C H Lucking
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Paraneoplastic Limbic Encephalitis
Psychosomatics, 2009Paraneoplastic limbic encephalitis (PLE) is a syndrome characterized by the development of neuropsychiatric symptoms due to a misdirected tumor-activated antibody response that damages host neural tissue. Definitive treatment relies on the identification and ablation of the underlying tumor.
Alison R, Foster, Jason P, Caplan
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Autoimmune limbic encephalitis
Acta Neurologica Scandinavica, 2009Autoimmune limbic encephalitis (LE) can arise both by paraneoplastic and non-paraneoplastic mechanisms. Patients with LE usually have a subacute onset of memory impairment, disorientation and agitation, but can also develop seizures, hallucinations and sleep disturbance.
C A, Vedeler, A, Storstein
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Neurology, 2008
Limbic encephalitis (LE) was initially described as a paraneoplastic syndrome characterized by rapid development of confusion, seizures, short-term memory loss, and high MRI T2 and FLAIR signal involving one or both medial temporal lobes.1 No more than 5 years ago, LE was considered to invariably have a paraneoplastic origin mostly associated with lung
Francesc Graus, Albert Saiz
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Limbic encephalitis (LE) was initially described as a paraneoplastic syndrome characterized by rapid development of confusion, seizures, short-term memory loss, and high MRI T2 and FLAIR signal involving one or both medial temporal lobes.1 No more than 5 years ago, LE was considered to invariably have a paraneoplastic origin mostly associated with lung
Francesc Graus, Albert Saiz
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Thymoma and Limbic Encephalitis
The Primary Care Companion For CNS Disorders, 2018To the Editor: Limbic encephalitis may have various causes and be associated with a number of neuropsychiatric disorders.1 Our knowledge of viral etiology, including herpes simplex virus, is quite advanced, but in autoimmune cases, our knowledge is still limited.
Ateş, Miruna Florentina +4 more
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