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Striatal hypermetabolism in limbic encephalitis [PDF]
Striatal hypermetabolism on 18FDG-PET scan is a neuroradiological finding that has been described in association with autoimmune disorders such as Sydenham chorea, lupus or antiphospholipid syndrome. Here, we report three patients with non-paraneoplastic limbic encephalitis characterized by 18FDG-PET hypermetabolism of both striata, in contrast with ...
Elsa Kaphan+6 more
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Limbic encephalitis – a review
Journal of Clinical Neuroscience, 2008The clinical features of limbic encephalitis are diverse and early diagnosis of the disorder is frequently difficult. Four patients with limbic encephalitis are described. An antineuronal antibody was identified in three of these patients. Antibodies directed against voltage-gated potassium channels, the N-methyl-D-aspartate receptor and an ...
Neil E Anderson, Peter Barber
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Autoimmune limbic encephalitis
Acta Neurologica Scandinavica, 2009Autoimmune limbic encephalitis (LE) can arise both by paraneoplastic and non-paraneoplastic mechanisms. Patients with LE usually have a subacute onset of memory impairment, disorientation and agitation, but can also develop seizures, hallucinations and sleep disturbance.
Christian A. Vedeler, Anette Storstein
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Neurosyphilis presenting as limbic encephalitis
BMJ Case Reports, 2023A man in his 50s presented with focal seizures and was found to have an inflammatory cerebrospinal fluid (CSF) with bilateral mesiotemporal lobe hyperintensity on magnetic resonance imaging (MRI) of the brain. Corticosteroid treatment was initiated for management of limbic encephalitis.
Matthew Shrimpton, Abhishek Malhotra
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Autoimmune Limbic Encephalitis
2019Autoimmune encephalitis is now being widely recognized as a common and potentially treatable cause of encephalitis. The majority of the autoimmune encephalitis cases clinically present with limbic system dysfunction. Many neural autoantibody biomarkers of autoimmune limbic encephalitis have been described, and novel antibodies are being recognized ...
Divyanshu Dubey+2 more
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Limbic encephalitis: a case report
Epilepsy Research, 1994We report a case of a 24 year old patient, who presented with simple and complex partial epileptic seizures, progressive changes in behaviour and affect including marked aggression, and a decline in memory to the point of inability to learn. Extensive work-up resulted in a final diagnosis of limbic encephalitis. This diagnosis was supported by a number
Nadia Khan, Heinz Gregor Wieser
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Serial MRI of limbic encephalitis
Neuroradiology, 2006The aim of the study was to analyze serial magnetic resonance imaging (MRI) scans in patients with various forms of limbic encephalitis (LE) in order to evaluate whether, and at what time point, MRI findings support the diagnosis of LE.Serial MRI scans (1 day to 15 years after the onset of symptoms) of 20 patients with LE were retrospectively evaluated.
Monika Jeub+5 more
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Herpes encephalitis and paraneoplastic limbic encephalitis
Neuropathology, 1998Pathological examination of four autopsy cases of herpes simplex virus encephalitis reconfirmed that the inflammatory necrotizing lesions occurred predominantly in the limbic system. This site predilection can be explained by the viral spread via the olfactory pathway, or along the meningeal branches of the trigeminal nerves and by the localization of ...
Kazuo Nagashima+4 more
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Neurology, 2008
Limbic encephalitis (LE) was initially described as a paraneoplastic syndrome characterized by rapid development of confusion, seizures, short-term memory loss, and high MRI T2 and FLAIR signal involving one or both medial temporal lobes.1 No more than 5 years ago, LE was considered to invariably have a paraneoplastic origin mostly associated with lung
Francesc Graus, Albert Saiz
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Limbic encephalitis (LE) was initially described as a paraneoplastic syndrome characterized by rapid development of confusion, seizures, short-term memory loss, and high MRI T2 and FLAIR signal involving one or both medial temporal lobes.1 No more than 5 years ago, LE was considered to invariably have a paraneoplastic origin mostly associated with lung
Francesc Graus, Albert Saiz
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Limbic encephalitis associated with systemic sclerosis
Multiple Sclerosis and Related Disorders, 2018We report the case of a patient affected by systemic sclerosis (SSc) who developed autoimmune limbic encephalitis, which improved under immunosuppressant agents and high-dose intravenous immunoglobulins. In our patient the autoimmune encephalitis occurred during apparently quiescent SSc, though concomitantly with novel arthritis.
De Stefano, Pia+3 more
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