Results 41 to 50 of about 9,160 (237)

A case of anti-VGKC antibody encephalitis and prolonged encephalopathy despite spontaneous resolution of imaging abnormalities

Journal of Community Hospital Internal Medicine Perspectives, 2020
Anti-voltage-gated potassium channel (anti-VGKC) antibody encephalitis is a common form of autoimmune encephalitis (AE). AE is usually associated with autoimmune diseases or paraneoplastic phenomena such as seen in small cell lung cancer.
Victoria Novoselova, Vikas Kumar, Niranjan N. Singh, Alexandre Lacasse   +3 more
doaj   +1 more source

Invasion of small cell lung cancer into the limbic system from leptomeningeal metastases

Respiratory Medicine Case Reports, 2021
The diagnosis of leptomeningeal metastases is sometimes difficult when the cytology of cerebrospinal fluid is negative. We report a rare case of leptomeningeal metastases that required differentiation from paraneoplastic limbic encephalitis.
Hisao Higo, Takuro Igawa, Katsuhiro Matsuoka, Hiromichi Kawaji, Noriyuki Suzaki, Takuya Nagata, Masako Nagayama, Masaomi Marukawa   +7 more
doaj   +1 more source

Immune checkpoint inhibitor-induced autoimmune limbic encephalitis with positivity for anti-Hu antibodies in a patient with small-cell lung cancer: A case report and literature review. [PDF]

Respirol Case Rep
Nakahara L, Matsuura S, Suzuki R, Kawamura A, Nagasaki T, Masuda T, Yamada K, Nakamura R, Hiramatsu T, Akiyama N, Tanaka K, Koshimizu N, Igasaki S.   +12 more
europepmc   +2 more sources

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye, Zu‐Ying Kuang, Bo Li, Meng‐Qiu Pan, Li‐Hua Zhou, Yang‐Yang Dai, Si‐Fen Xie, Xian‐Guang Lin, Ye‐Peng Hu, Li‐Hong Jiang, Zhan‐Hang Wang, Wei‐Jing Zhang   +11 more
wiley   +1 more source

Paraneoplastic limbic encephalitis revealing a small cell carcinoma of the lung

Respiratory Medicine Case Reports, 2019
Introduction: Paraneoplastic limbic encephalitis is a rare disease, usually associated with small cell lung cancer. Case report: We report in this publication the cases with different age brackets, who presented with various neurological symptoms such as
Marwa Kacem, Nidhal Belloumi, Imene Bachouche, Mariem Mersni, Fatma Chermiti Ben Abdallah, Soraya Fenniche   +5 more
doaj   +1 more source

Neuroinflammation in GAD65 Antibody‐Associated Epilepsy Measured Using [18F]DPA‐714 PET/MRI

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The timing for initiating immunotherapy in patients with glutamic acid decarboxylase 65 (GAD65) antibody‐associated epilepsy is a challenge. We used the translocator protein radioligand [18F]DPA‐714 and PET to evaluate brain microglial activation.
Jingjing Chen, Yuying Zhang, Heyu Zhang, Jinming Zhang, Ningning Wang, Xintong Guo, Yicong Liu, Yue Liu, Xiangsong Zhang, Ziyi Chen, Guanzhong Ni   +10 more
wiley   +1 more source

A Patient with Anti-LGI1 Related Autoimmune Limbic Encephalitis who had Frequent and Drug Resistant Seizures

Archives of Epilepsy, 2016
Anti-LGI1 auto-antibody related limbic encephalitis is characterized by memory deficits, various neuro-psychiatric symptoms, behavioral disorders and temporal lobe seizures that point to involvement of the limbic system.
Neşe DERİCİOĞLU
doaj   +1 more source

Toxic Epidermal Necrolysis in a Patient with Autoimmune Limbic Encephalitis with Anti-Glutamate Receptor Antibodies

Case Reports in Neurology, 2018
We report on a 44-year-old woman who was diagnosed with toxic epidermal necrolysis (TEN) during the recovery phase from autoimmune limbic encephalitis with anti-glutamate receptor antibodies.
Keiko Hatano, Hideyuki Matsumoto, Akihiko Mitsutake, Junko Yoshimura, Aya Nomura, Sumihisa Imakado, Yukitoshi Takahashi, Hideji Hashida   +7 more
doaj   +1 more source

Minimally Clinically Important Difference of the Clinical Assessment Scale in Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The Clinical Assessment Scale in Autoimmune Encephalitis (CASE) tracks disease severity in autoimmune encephalitis (AE), but no threshold for significant change exists. We aimed to determine the minimally clinically important difference (MCID) for CASE.
Yihui Goh, Yoon Hee Shin, Soo Hyun Ahn, Su Yee Mon, Soo Jean Shin, Woo‐Jin Lee, Yoonhyuk Jang, Myoung‐Jin Jang, Soon‐Tae Lee   +8 more
wiley   +1 more source

Selective Limbic Blood–Brain Barrier Breakdown in a Feline Model of Limbic Encephalitis with LGI1 Antibodies

Frontiers in Immunology, 2017
Human leucine-rich glioma-inactivated protein 1 encephalitis (LGI1) is an autoimmune limbic encephalitis in which serum and cerebrospinal fluid contain antibodies targeting LGI1, a protein of the voltage gated potassium channel (VGKC) complex.
Anna R. Tröscher, Andrea Klang, Maria French, Lucía Quemada-Garrido, Sibylle Maria Kneissl, Christian G. Bien, Ákos Pákozdy, Jan Bauer   +7 more
doaj   +1 more source