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Autoimmune Limbic Encephalitis: A Review of Clinicoradiological Features and the Challenges of Diagnosis

Cureus, 2021
Limbic encephalitis is an autoimmune cause of encephalitis. In addition to the usual symptoms of encephalitis such as altered consciousness, fever, and focal neurological deficits, limbic encephalitis can present with neuropsychiatric manifestations and ...
Jack B. Ding, J. Dongas, Kevin Hu, Mark Ding   +3 more
semanticscholar   +1 more source

Neuropsychological Evaluations in Limbic Encephalitis

Brain Science, 2021
Limbic encephalitis (LE) can cause dynamic and permanent impairment of cognition and behavior. In clinical practice, the question arises as to which cognitive and behavioral domains are affected by LE and which assessment is suited to monitor the disease
J. Witt, C. Helmstaedter
semanticscholar   +1 more source

Determinants of cognition in autoimmune limbic encephalitis—A retrospective cohort study

Hippocampus, 2021
Autoimmune limbic encephalitis (ALE) is the most common type of autoimmune encephalitis (AIE). Subacute memory disturbance, temporal lobe seizures, and psychiatric symptoms are clinical hallmarks of the disease.
C. Mueller, L. Langenbruch, Johanna M H Rau, T. Brix, C. Strippel, A. Dik, Kristin S. Golombeck, C. Moenig, Saskia Räuber, S. Kovac, H. Wiendl, S. Meuth, Jens Bölte, A. Johnen, N. Melzer   +14 more
semanticscholar   +1 more source

Neuronal Surface Antibody-Medicated Autoimmune Encephalitis (Limbic Encephalitis) in China: A Multiple-Center, Retrospective Study

Frontiers in Immunology, 2021
Objective: The epidemiological characteristics of patients with antibody-medicated autoimmune encephalitis in China remain unclear, and a large-scale epidemiological survey is necessary. Methods: A multiple-center retrospective study was performed.
Wei Shan, Huajun Yang, Qun Wang
semanticscholar   +1 more source

T1w/T2w Ratio Identifies the Basolateral Amygdala as a Preferential Target in Autoimmune Limbic Encephalitis. [PDF]

J Neuroimaging
ABSTRACT Background and Purpose The amygdala plays a key role in the pathophysiology of autoimmune limbic encephalitis (ALE), contributing to epileptic seizures and neuropsychiatric symptoms. While no study has examined microstructural changes in individual amygdala nuclei in ALE, we used the T1‐weighted/T2‐weighted (T1w/T2w) ratio to explore amygdalar
Dadarwal R, Dik A, Bierhansl L, Gmahl N, Landmeyer NC, Brix TJ, Jaeger VK, Bauer J, Küker W, Wiendl H, Elger CE, Kovac S, Bischof A.   +12 more
europepmc   +2 more sources

Scrub Typhus Masquerading as Limbic Encephalitis

The Neurohospitalist, 2021
Scrub typhus, an acute febrile infectious disease prevalent in the ‘tsutsugamushi triangle’, is a mite-born rickettsial zoonosis, caused by Orientia tsutsugamushi.
S. Biswas, R. Ghosh, D. Roy, A. Ray, Kaustav De, Subrata Biswas, Dinabandhu Naga, J. Benito‐León   +7 more
semanticscholar   +1 more source

ANTI-MA2 encephalitis mimicking diencephalic demyelinating syndrome

Interdisciplinary Neurosurgery, 2021
Anti Ma 2 encephalitis is an autoimmune encephalitis, usually paraneoplastic, characterized by isolated or combined limbic, diencephalic, or brainstem dysfunction. Limbic encephalitis (LE) is the most common manifestation.
Agábio Diógenes Pessoa Neto, Bárbara Cristina Vieira de Aquino, Paulo Santiago de Morais Brito, Rodrigo de Alencar e Silva, Manuel Moreira Neto, Orlando Graziani Povoas Barsottini, Lívia Almeida Dutra, Clécio de Oliveira Godeiro Junior   +7 more
doaj   +1 more source

Leucine-rich glioma-inactivated protein 1 antibody-positive limbic encephalitis in a patient with an early-stage asymptomatic breast cancer. [PDF]

BMJ Case Rep
Niño Uribe MF, Van Cutsem G, Kerschen P.   +2 more
europepmc   +3 more sources

Diagnostic challenges in patients with temporal lobe seizures and features of autoimmune limbic encephalitis

European Journal of Neurology, 2021
Consensus criteria for autoimmune limbic encephalitis (ALE) allow for a diagnosis even without neuronal antibodies (Abs), but it remains unclear which clinical features should prompt neuronal Ab screening in temporal lobe epilepsy patients.
F. Ismail, Marianna Spatola, F. Woermann, S. Popkirov, Johannes Jungilligens, C. Bien, J. Wellmer, U. Schlegel   +7 more
semanticscholar   +1 more source

Paraneoplastic encephalitis associated with renal cell carcinoma [PDF]

Encephalitis, 2021
Purpose Paraneoplastic encephalitis is autoimmune encephalitis accompanied by tumors. Renal cell carcinoma (RCC) is a kidney cancer originating from various types of renal cells and rarely has been associated with paraneoplastic neurologic manifestation.
Yoonhyuk Jang, SeonDeuk Kim, Kon Chu, Sang Kun Lee, Soon-Tae Lee   +4 more
doaj   +1 more source