Results 161 to 170 of about 11,756,332 (389)
Surpassing the lateral resolution limit by a factor of two using structured illumination microscopy
M. Gustafsson
semanticscholar +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Language Identification in the Limit
E. Gold
semanticscholar +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
V doktorski disertaciji se obravnava vprašanje ali iz konvergence grafov navzgor polzveznih veznih funkcij sledi konvergenca ustreznih pripadajočih inverznih limit za konstantna inverzna zaporedja kompaktnih metričnih prostorov. V uvodnem delu se vpeljejo osnovni pojmi kot so navzgor polzvezne funkcije, inverzna zaporedja in inverzne limite.
openaire +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source

