Computation of bounds for anchor problems in limit analysis and decomposition techniques [PDF]
, 2013 Numerical techniques for the computation of strict bounds in limit analyses have been developed for more than thirty years. The efficiency of these techniques have been substantially improved in the last ten years, and have been successfully applied ...
Huerta, Antonio +3 more
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
The Validity of Benchmark Dose Limit Analysis for Estimating Permissible Accumulation of Cadmium. [PDF]
Int J Environ Res Public Health, 2022 Satarug S +3 more
europepmc +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Evaluation method of surrounding rock stability: Failure approach index theory of strain limit analysis for engineering applications. [PDF]
PLoS One, 2022 Xiong L +6 more
europepmc +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Forming Limit Analysis of Thin-Walled Extruded Aluminum Alloy Tubes under Nonlinear Loading Paths Using an Improved M-K Model. [PDF]
Materials (Basel), 2023 Zhu H, Lin Y, Chen K, He Z.
europepmc +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Integrated Neural Based System for State Estimation and Confidence Limit Analysis in Water Networks [PDF]
, 1997 In this paper a simple recurrent neural network (NN) is used as a basis for constructing an integrated system capable of finding the state estimates with corresponding confidence limits for water distribution systems.
Bargiela, Andrzej, Gabrys, Bogdan
core
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source