Results 61 to 70 of about 2,230,220 (315)
On the limits of probabilistic timing analysis
, 2023 Over the last years, we are witnessing the steady and rapid growth of Critica! Real-Time Embedded Systems (CRTES) industries, such as automotive and aerospace. Many of the increasingly-complex CRTES' functionalities that are currently implemented with mechanical means are moving towards to an electromechanical implementation controlled by critica ...
openaire +4 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
On the ratchet analysis of a cracked welded pipe [PDF]
, 2011 This paper presents the ratchet limit analysis of a pipe with a symmetric crack in a mismatched weld by using the extended Linear Matching Method (LMM). Two loading conditions are considered: i) a cyclic temperature load and a constant internal pressure;
Ure, James Michael +7 more
core +1 more source
Diagnosis and Seismic Behavior Evaluation of the Church of São Miguel de Refojos (Portugal)
Buildings, 2019 The Benedictine Monastery of São Miguel de Refojos, located in Cabeceiras de Basto (Portugal), is a monumental complex and a distinctive example of the 18th century Portuguese Baroque architecture.
Rafael Ramírez +2 more
doaj +1 more source
Value and limitation of meta-analysis [PDF]
Pathophysiology of Haemostasis and Thrombosis, 2002 Meta-analysis is a valuable method of aggregating data sets of different trials which are inadequate or unconvincing on their own. There are strict rules on the retrieval and selection of data which are crucial in terms of the validity of a meta-analysis. Many so-called meta-analyses are flawed because of lack of a protocol or non adherence to it. Also
openaire +2 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Unilateral contact and damage analysis in masonry arches
Vietnam Journal of Mechanics, 2009 In the present work the ultimate failure load and the collapse mechanism of a stone arch bridge are estimated by the usage of (a) a multi - part elastic model with unilateral contact frictional interfaces and (b) a continuous damage model.
M. Campo +2 more
doaj +1 more source
R-adaptivity in Limit Analysis
, 2017 Direct methods aim to find the maximum load factor that a domain made of a plastic material can sustain before undergoing full collapse. Its analytical solution may be posed as a constrained maximisation problem, which is computationally solved by resorting to appropriate discretisation of the relevant fields such as the stress or velocity fields.
Muñoz Romero, José +2 more
openaire +3 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source