Results 71 to 80 of about 2,230,220 (315)
Face stability of shield-driven tunnels using multi-tangent technique
Yantu gongcheng xuebaoTo address the face stability problem of deep-buried tunnels under nonlinear conditions, using Power-Law (P-L) criterion the approximate piecewise and by multi-tangent technique, a novel multi-cone failure mechanism is developed for tunnel faces based on
ZHONG Junhao1, 2 , CHIAN Siau Chen2, LI Yongxin3, LIU Mingfang4, CHEN Minghui4, WU Zhenyuan4, LONG Guihua4, YANG Xiaoli1, ZHOU De1
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The speed of limit order execution in the Spanish stock exchange [PDF]
, 2005 The objective of this work is to study empirically the factors influencing the execution time in the Spanish Stock Exchange. Our dataset includes the orders and transactions of the assets belonging to IBEX 35 in the period between July and September 2000.
Gava, Luana
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
, 1976 Trockel W. A limit theorem on the core. Journal of Mathematical Economics.
Walter Trockel +1 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Passive earth pressure analysis of berm-retained excavation by upper bound method
Yantu gongcheng xuebao, 2020 The passive earth pressure should be known for the design of the berm-retained excavation, but no reasonable method for calculating the passive earth pressure has been found until now. According to the characteristics of the berm-retained excavation, the
QIN Hui-lai 1, ZHOU Yu-qi 1, HUANG Mao-song 2, ZHOU Tong-he 3
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source