Results 101 to 110 of about 564,884 (264)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Quantum thermodynamics on a limit cycle
Quantum Science and TechnologyAbstract We consider a periodic quantum clock based on cooperative resonance fluorescence at zero temperature. The semi-classical dynamics exhibit a Hopf bifurcation to a limit cycle. In the quantum case, this system has an exact steady state and the limit cycle appears in conditional quantum dynamics under homodyne detection. We show
Varinder Singh +2 more
openaire +4 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Computation of focal values and stability analysis of 4-dimensional systems
Electronic Journal of Differential Equations, 2015 This article presents a recursive formula for computing the n-th singular point values of a class of 4-dimensional autonomous systems, and establishes the algebraic equivalence between focal values and singular point values. The formula is linear and
Bo Sang, Qin-Long Wang, Wen-Tao Huang
doaj
Homoclinic and Heteroclinic Neural ODEs: Theory and Its Use to Construct New Chaotic Attractors
Journal of Optimization, Differential Equations and Their ApplicationsNew types of neural ordinary differential equations (NODE) with power nonlinearities are considered. For these NODE systems, new conditions for the existence of homoclinic and heteroclinic orbits are found.
Vasiliy Ye. Belozyorov +2 more
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Correction for restoring force in mass measurement using dead-zone relay feedback of displacement
Mechanical Engineering JournalIn a mass measurement system using relay feedback of displacement, an object to be measured was guided mechanically by leaf springs to restrict its motion to a single translation.
Takeshi MIZUNO +4 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source