Results 81 to 90 of about 2,178,559 (245)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Complex dynamics in biological systems arising from multiple limit cycle bifurcation

open access: yesJournal of Biological Dynamics, 2016
In this paper, we study complex dynamical behaviour in biological systems due to multiple limit cycles bifurcation. We use simple epidemic and predator–prey models to show exact routes to new types of bistability, that is, bistability between equilibrium
P. Yu, W. Lin
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A Simple Predator-Prey Population Model with Rich Dynamics

open access: yesApplied Sciences, 2016
A non-smooth switched harvest on predators is introduced into a simple predator-prey model with logistical growth of the prey and a bilinear functional response.
Bing Li   +3 more
doaj   +1 more source

Limit-Cycle Properties of a Rijke Tube [PDF]

open access: yes, 2003
Thermoacoustic instability appears when unsteady heat release is favourably coupled with acoustic pressure perturbations. The important technical applications involving thermoacoustics are combustion instability in rocket motors and low-pollutant lean ...
Culick, F. E. C., Matveev, K. I.
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Three crossing limit cycles in planar piecewise linear systems with saddle-focus type

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2015
This paper presents an analysis on the appearance of limit cycles in planar Filippov system with two linear subsystems separated by a straight line. Under the restriction that the orbits with points in the sliding and escaping regions are not considered,
Liping Li
doaj   +1 more source

Synchronization of spin-driven limit cycle oscillators optically levitated in vacuum. [PDF]

open access: yesNat Commun, 2023
Brzobohatý O   +7 more
europepmc   +1 more source

Off-diagonal long-range order, cycle probabilities, and condensate fraction in the ideal Bose gas

open access: yes, 2007
We discuss the relationship between the cycle probabilities in the path-integral representation of the ideal Bose gas, off-diagonal long-range order, and Bose--Einstein condensation.
E. H. Lieb   +8 more
core   +1 more source

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