Results 61 to 70 of about 2,178,559 (245)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
The Stability for Limit Cycle of Lomax Autoregressive Model
Tikrit Journal of Pure ScienceIn this research, we proposed a new non-linear model known as the Lomax autoregressive model, which is based on the cumulative distribution function of the Lomax distribution. Using the local linearization approximation technique, we found stability for
Ruya K. Abbas, Azher A. Mohammed
doaj +1 more source
Collective phase synchronization in locally-coupled limit-cycle oscillators
, 2003 We study collective behavior of locally-coupled limit-cycle oscillators with scattered intrinsic frequencies on $d$-dimensional lattices. A linear analysis shows that the system should be always desynchronized up to $d=4$.
A. Pikovsky +7 more
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
, 2011 For the first time ever, we derive equations governing the time-evolution of fully relativistic slim accretion disks in the Kerr metric, and numerically construct their detailed non-stationary models. We discuss applications of these general results to a
Abramowicz +32 more
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Explicit limit cycles of a family of polynomial differential systems
Electronic Journal of Differential Equations, 2017 We consider the family of polynomial differential systems $$\displaylines{ x' = x+( \alpha y-\beta x) (ax^2-bxy+ay^2) ^{n}, \cr y' = y-( \beta y+\alpha x) (ax^2-bxy+ay^2) ^{n}, }$$ where a, b, $\alpha $, $\beta $ are real constants and n is ...
Rachid Boukoucha
doaj
Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
wiley +1 more source