Results 121 to 130 of about 6,209,872 (360)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
PMA models for nonlinear control: Nonlinear Damping and Limit-Cycle Induction for Reference Tracking
Luka Eciolaza +2 more
openalex +1 more source
Attractive holomorphic limit cycles
This work deals with a problem which is, in a way, an opposite of the Reeb-Haefliger conjecture. The manifold \(X\) need not to be compact here, but it is assumed to be connected and to have a countable base. Holomorphic foliations on connected, complex manifolds are studied just like dynamical systems (thus limit sets, limit cycles, attractors etc ...
openaire +2 more sources
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Self-Ordered Limit Cycles, Chaos, and Phase Slippage with a Superfluid inside an Optical Resonator [PDF]
Francesco Piazza, Helmut Ritsch
openalex +1 more source
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Cubic and quartic planar differential systems with exact algebraic limit cycles
We construct cubic and quartic polynomial planar differential systems with exact limit cycles that are ovals of algebraic real curves of degree four. The result obtained for the cubic case generalizes a proposition of [9].
Ahmed Bendjeddou, Rachid Cheurfa
doaj
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Self-sustained Oscillations and Limit Cycles in Rayleigh System with Cubic Return Force
S. A. Kumakshev
openalex +2 more sources
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source

