Results 51 to 60 of about 1,086,889 (297)

The long-time dynamics of two hydrodynamically-coupled swimming cells [PDF]

open access: yes, 2009
Swimming micro-organisms such as bacteria or spermatozoa are typically found in dense suspensions, and exhibit collective modes of locomotion qualitatively different from that displayed by isolated cells.
A. Czirok   +53 more
core   +3 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Simplified approach for locating the critical probabilistic slip surface in limit equilibrium analysis [PDF]

open access: yesNatural Hazards and Earth System Sciences, 2015
This paper aims to develop a rapid and practical procedure that can locate the slip surface for a slope with the minimum reliability index for limit equilibrium analysis at the minimum expense of time.
Y. M. Cheng, L. Li, L. L. Liu
doaj   +1 more source

How Bad is Forming Your Own Opinion? [PDF]

open access: yes, 2011
The question of how people form their opinion has fascinated economists and sociologists for quite some time. In many of the models, a group of people in a social network, each holding a numerical opinion, arrive at a shared opinion through repeated ...
Bindel, David   +2 more
core   +4 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The problems of limit load analysis and optimization using equilibrium finite elements

open access: yesJournal of Civil Engineering and Management, 1996
The equilibrium dual discrete mathematical models of the problems of limit load analysis and optimization are investigated in the article. These models are presented in terms of static and kinematic formulation using equilibrium finite elements. In these
Stanislovas Kalanta
doaj   +1 more source

Stability Analysis of a Multi-Layered Slope in an Open Pit Mine

open access: yesGeosciences, 2023
The design of slopes in open pit mines requires an in-depth understanding of the ground behavior to predict the potential failure mechanism and to better determine the stabilization measures.
Emmanouil Steiakakis   +4 more
doaj   +1 more source

High Order Asymptotic Preserving DG-IMEX Schemes for Discrete-Velocity Kinetic Equations in a Diffusive Scaling [PDF]

open access: yes, 2013
In this paper, we develop a family of high order asymptotic preserving schemes for some discrete-velocity kinetic equations under a diffusive scaling, that in the asymptotic limit lead to macroscopic models such as the heat equation, the porous media ...
Jang, Juhi   +3 more
core  

Rouse Chains with Excluded Volume Interactions: Linear Viscoelasticity

open access: yes, 2000
Linear viscoelastic properties for a dilute polymer solution are predicted by modeling the solution as a suspension of non-interacting bead-spring chains.
Bird R. B.   +18 more
core   +3 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

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