Results 71 to 80 of about 1,086,889 (297)

Limit equilibrium analysis of translational failure of landfills under different leachate buildup conditions

open access: yesWater Science and Engineering, 2008
Excessive leachate levels in landfills can be a major triggering mechanism for translational failure. The scope of this paper is to present the development of the calculation methods for limit equilibrium analysis of translational failure of landfills ...
Qian Xuede
doaj   +3 more sources

Linear and non-linear thermodynamics of a kinetic heat engine with fast transformations

open access: yes, 2016
We investigate a kinetic heat engine model constituted by particles enclosed in a box where one side acts as a thermostat and the opposite side is a piston exerting a given pressure.
Cerino, Luca   +2 more
core   +1 more source

Dissipative periodic and chaotic patterns to the KdV--Burgers and Gardner equations [PDF]

open access: yes, 2019
We investigate the KdV-Burgers and Gardner equations with dissipation and external perturbation terms by the approach of dynamical systems and Shil'nikov's analysis.
Adams, Ronald, Mancas, Stefan C.
core   +3 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Calculating the Bearing Capacity of Foundations near Slopes Based on the Limit Equilibrium and Limit Analysis Methods

open access: yesBuildings
The ultimate bearing capacity of foundations near slopes is a widely discussed and researched topic in the field of geotechnics. Using the plane strain strength equation of the limit equilibrium and limit analysis methods, we established a new model for ...
Mulang Ye, Hua Tang
doaj   +1 more source

Optimal scaling for the transient phase of Metropolis Hastings algorithms: The longtime behavior

open access: yes, 2014
We consider the Random Walk Metropolis algorithm on $\mathbb{R}^n$ with Gaussian proposals, and when the target probability measure is the $n$-fold product of a one-dimensional law. It is well known (see Roberts et al. (Ann. Appl. Probab.
Jourdain, Benjamin   +2 more
core   +2 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Analysis method for limit displacement based on displacement-associated stability of piled soil slopes

open access: yesYantu gongcheng xuebao
The classic limit equilibrium method cannot make a connection between slope stability and its displacement, and does not solve the limit displacement for the slope from a stable state to the limit state.
WU Bing1 , LI Shaohong2, XIAO Shiguo2 , LIANG Yao3
doaj   +1 more source

Discreteness-Induced Slow Relaxation in Reversible Catalytic Reaction Networks

open access: yes, 2010
Slowing down of the relaxation of the fluctuations around equilibrium is investigated both by stochastic simulations and by analysis of Master equation of reversible reaction networks consisting of resources and the corresponding products that work as ...
A. Goldbeter   +3 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

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