Results 81 to 90 of about 1,086,889 (297)

Application and comparison of stability analysis of slope using circular arc method and strength reduction method

open access: yesMATEC Web of Conferences, 2016
In order to evaluate the accuracy of strength reduction method using FEM, the safety factors of the uniform clay slope and sand slope are investigated by Fellenius’s method, Bishop’s method using traditional limit equilibrium method and strength ...
Xu Bin Bin, Xie Lin Bo, Si Wei
doaj   +1 more source

Renormalization Group Flow of the Two-Dimensional Hierarchical Coulomb Gas

open access: yes, 2000
We consider a quasilinear parabolic differential equation associated with the renormalization group transformation of the two-dimensional hierarchical Coulomb system in the limit as the size of the block L goes to 1.
Guidi, Leonardo F.   +1 more
core   +1 more source

Virtual Testing of Experimental Continuation [PDF]

open access: yes, 2018
We present a critical advance in experimental testing of nonlinear structures. Traditional quasi-static experimental methods control the displacement or force at one or more load-introduction points on a structure.
Groh, Rainer M. J.   +3 more
core   +3 more sources

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Universal post-quench coarsening and quantum aging at a quantum critical point

open access: yes, 2015
The non-equilibrium dynamics of a system that is located in the vicinity of a quantum critical point is affected by the critical slowing down of order-parameter correlations with the potential for novel out-of-equilibrium universality.
Gagel, Pia   +2 more
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Analytical modelling and the minimum thickness of three-centred arches

open access: yesInformes de la Construccion
Equilibrium analyses of vaulted masonry structures, as well as the mathematical modelling of their structural behaviour, have gained prominence within researches on both historic structures and novel digitally fabricated designs. Thus, by revisiting the
Dimitriye Nikolich
doaj   +1 more source

Variational Convergence of Discrete Geometrically-Incompatible Elastic Models

open access: yes, 2018
We derive a continuum model for incompatible elasticity as a variational limit of a family of discrete nearest-neighbor elastic models. The discrete models are based on discretizations of a smooth Riemannian manifold $(M,\mathfrak{g})$, endowed with a ...
Kupferman, Raz, Maor, Cy
core   +1 more source

Limit Equilibrium Slope Stability Analysis Considering Progressive Failure

open access: yesLandslides, 1997
This paper proposes a slope stability analysis method considering progressive failure based on the limit equilibrium principle. The softening of soil is taken into account and the slip surface of arbitary shape is adopted.Formulation of the ploblem is carried out by using the slice method, and the analysis satisfies both force and moment equilibrium ...
Masakazu TAKI, Takuo YAMAGAMI
openaire   +2 more sources

Home - About - Disclaimer - Privacy