Results 201 to 210 of about 2,451,911 (303)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Immunological assay using a solid-state pore with a low limit of detection. [PDF]

Sci Rep
Takei H, Nakada T, Leong LW, Ito A, Hanada K, Maeda H, Sohail MS, Tomiyasu K, Sakamoto O, Naono N, Taniguchi M.   +10 more
europepmc   +1 more source

The Limit of Detection Matters: The Case for Benchmarking Severe Acute Respiratory Syndrome Coronavirus 2 Testing. [PDF]

Clin Infect Dis, 2021
Arnaout R, Lee RA, Lee GR, Callahan C, Cheng A, Yen CF, Smith KP, Arora R, Kirby JE.   +8 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

marlod: an R package to model environmental exposure and biomonitoring data with repeated measurements and values below the limit of detection. [PDF]

J Expo Sci Environ Epidemiol
Chen IC.
europepmc   +1 more source

Low limit of detection of the AlGaN/GaN-based sensor by the Kelvin connection detection technique. [PDF]

Microsyst Nanoeng, 2021
Zhang H, Gan Y, Yang S, Sheng K, Wang P.
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Clinical utility of companion diagnostic biomarker results below the limit of detection in comprehensive genomic profiling of patients with advanced non-small cell lung cancer. [PDF]

Oncologist
Li G, Greene SB, Kaur B, Keller-Evans RB, Graf RP, Decker B, Smith DL, Huang RSP.   +7 more
europepmc   +1 more source

A handheld luminometer with sub-attomole limit of detection for distributed applications in global health

, 2023
Lebel P, Elledge S, Wiener DM, Jeyakumar I, Phelps M, Jacobsen A, Huynh E, Charlton C, Puccinelli R, Mondal P, Saha S, Tato CM, Gómez-Sjöberg R.   +12 more
europepmc   +1 more source

Correction to: Low limit of detection of the AlGaN/GaN-based sensor by the Kelvin connection detection technique. [PDF]

Microsyst Nanoeng, 2021
Zhang H, Gan Y, Yang S, Sheng K, Wang P.
europepmc   +1 more source