Results 181 to 190 of about 2,451,911 (303)

Ultra-low limit of detection of a carcinoembryonic antigen fiber sensor based on microfiber. [PDF]

Biomed Opt Express
Wan J, Wang S, Zhou S, Qiu H, Lu R, Jiang M, Li J, Huang Y, Cai L.   +8 more
europepmc   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Commonly Used Alkylating Agents Limit Persulfide Detection by Converting Protein Persulfides into Thioethers. [PDF]

Angew Chem Int Ed Engl, 2022
Schilling D, Barayeu U, Steimbach RR, Talwar D, Miller AK, Dick TP.   +5 more
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Diagnostic accuracy and limit of detection of ten malaria parasite lactate dehydrogenase-based rapid tests for Plasmodium knowlesi and P. falciparum. [PDF]

Front Cell Infect Microbiol, 2022
Tan AF, Sakam SSB, Rajahram GS, William T, Abd Rachman Isnadi MF, Daim S, Barber BE, Kho S, Sutherland CJ, Anstey NM, Yerlikaya S, van Schalkwyk DA, Grigg MJ.   +12 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Improvement of the optical cavity-based biosensor's limit of detection using optimal 3-aminopropyltriethoxysilane process. [PDF]

Sci Rep
Sypabekova M, Kleiss J, Hagemann A, Schuemann S, Wills R, Zechmann B, Kim S.   +6 more
europepmc   +1 more source

Study of the Sensitivity Limit of Detection of α-Particles by Polymer Film Detectors LR-115 Type 2 Using X-ray Diffraction and UV-Vis Spectroscopic Methods. [PDF]

Polymers (Basel), 2023
Yerimbetova DS, Kozlovskiy AL, Tuichiyev UN, Zhumadilov KS.   +3 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Analytical validation (accuracy, reproducibility, limit of detection) and gene expression analysis of FoundationOneRNA assay for fusion detection in 189 clinical tumor specimens. [PDF]

PLoS One
Sun D, Huang RSP, Green M, Cui C, Sisoudiya SD, Savol A, Xu C, Guo C, Skoletsky J, Allen JM, Tolba K, Pattani V, Tarzia A, Whiting J, Tang Y, Albacker LA, Vietz C, Datto M, He J, Jeck WR.   +19 more
europepmc   +1 more source