Results 151 to 160 of about 5,100 (188)

Understanding Consumption of Illicit Drugs and New Psychoactive Substances in Australia by Triangulating Drug Checking and Wastewater‐Based Epidemiology

open access: yesDrug Testing and Analysis, EarlyView.
First Australian study combining wastewater‐based epidemiology and drug checking, demonstrating how complementary data sources enhance monitoring of illicit drugs and emerging psychoactive substances during high‐use periods. ABSTRACT Consumption of psychotropic drugs is a major economic and public health challenge in Australia.
Muhammad Usman   +8 more
wiley   +1 more source

Micro‐QuEChERS Extraction for Broad‐Spectrum LC‐QQQ‐MS Quantification of Nitazene Analogs in Plasma: A Validated Method With Casework Application

open access: yesDrug Testing and Analysis, EarlyView.
Micro‐QuEChERS sample preparation coupled to LC‐QQQ‐MS enabled sensitive quantification of nitazene analogs in 100 μL of plasma. The validated method provided low detection limits and was successfully applied to an authentic intoxication case involving N‐pyrrolidino protonitazene, supporting clinical and forensic toxicology workflows.
Karla A. O. Souza   +7 more
wiley   +1 more source

Quantification of the Carboxylated LGD‐4033 Long‐Term Metabolite in Human Micro‐Dose Excretion Study Urine Samples

open access: yesDrug Testing and Analysis, EarlyView.
A validated LC‐HRMS/MS method enabled the first quantitative determination of the LGD‐4033 long‐term metabolite (M5‐b) in urine following controlled micro‐dose administration. The generated urinary reference data support the interpretation of adverse analytical findings and anti‐doping result management. ABSTRACT Selective androgen receptor modulators (
Panagiotis Sakellariou   +7 more
wiley   +1 more source

Antidepressant Misuse in Esports: A Review of Pharmacology, Adverse Effects, Pharmacokinetics and Biomatrix‐Based Detection for Anti‐Doping Applications

open access: yesDrug Testing and Analysis, EarlyView.
This review highlights the misuse of antidepressants as potential cognitive‐enhancing agents in Esports. Despite pharmacological effects that overlap with those of psychostimulants, antidepressants remain an under‐recognised source of doping in Esports.
Kassim Ali Salum   +4 more
wiley   +1 more source

Detection of Nitazenes in the Illicit Drug Supply Utilizing Precursor Ion Scan Methods With Paper Spray Mass Spectrometry

open access: yesDrug Testing and Analysis, EarlyView.
Nitazenes are increasingly present in the illicit drug supply, complicating harm reduction efforts. We have developed a rapid, nontargeted precursor ion scan method to detect emerging nitazenes in real‐world opioid samples. The method identified multiple nitazenes, often replacing pharmaceutical opioids or mixed with fentanyl and benzodiazepines ...
Allie Miskulin   +6 more
wiley   +1 more source

Machine Learning–Enhanced Fluorescence Cryptography with NADH‐Responsive Polymer Dots

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This study presents a smart anticounterfeiting system using semiconducting polymer dots (Pdots) that exhibit tunable fluorescence responses to NADH. By integrating these dynamic optical signals with machine learning–based decoding, the work establishes a secure and intelligent encryption platform, showing a novel strategy that links chemical sensing ...
Zhengkun Zhan   +7 more
wiley   +1 more source

Highly Permeable CeO2 Porous Hollow Microspheres with Multilevel Gas Channels for Rapid NH3 Gas Response and Recovery Performance

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
In this study, a series of highly permeable CeO2 porous hollow microspheres with multilevel gas channels and tunable pore sizes were first prepared via the hydrothermal method, achieving rapid response and fast recovery to ammonia gas. Fast response and recovery performance is highly significant for real‐time monitoring of NH3 gas due to the toxic and ...
Mengke Li   +11 more
wiley   +1 more source

Flexible Direct‐Conversion X‐Ray Detectors: From Emerging Materials to Conformal Imaging

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This comprehensive review analyzed the performance, challenges, and future directions of four emerging material systems for next‐generation flexible direct‐conversion X‐ray detectors: organic semiconductors, perovskites, metal–organic frameworks, and inorganic metal compounds.
Haipeng Di   +11 more
wiley   +1 more source
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Detection Limit (LOD) and Limit of Quantification (LOQ) Using Microscopical Methods in Asbestos Analysis

2021
Optical methods (light or electron microscopy) are, in most cases, the basis for measuring the asbestos concentration either in air or in materials. The individual methods are described in a variety of guidelines or standards. The definition of terms like detection limit and analytical sensitivity have led to numerous discussions, driven by the fact ...
exaly   +2 more sources

Assessment of average of normals (AON) procedure for outlier-free datasets including qualitative values below limit of detection (LoD): an application within tumor markers such as CA 15-3, CA 125, and CA 19-9

Scandinavian Journal of Clinical and Laboratory Investigation, 2016
Average of normals (AON) is a quality control procedure that is sensitive only to systematic errors that can occur in an analytical process in which patient test results are used. The aim of this study was to develop an alternative model in order to apply the AON quality control procedure to datasets that include qualitative values below limit of ...
Murat Usta   +2 more
exaly   +5 more sources

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