Results 1 to 10 of about 56,277 (295)

Are LOD and LOQ Reliable Parameters for Sensitivity Evaluation of Spectroscopic Methods? [PDF]

Journal of AOAC INTERNATIONAL, 2018
Abstract The limit of detection (LOD) and the limit of quantification (LOQ) are common parameters to assess the sensitivity of analytical methods. In this study, the LOD and LOQ of previously reported terbium sensitized analysis methods were calculated by different methods, and the results were compared with sensitivity parameters [lower
Ali Shayanfar, Shayanfar Ali
exaly   +4 more sources

Influence of Chromatographic Conditions on LOD and LOQ of Fluoxetine and Sertraline Analyzed by TLC-Densitometric Method

Processes, 2022
This research introduces the analysis of fluoxetine and sertraline by means of the TLC-densitometric method. They provide information on LOD and LOQ under various chromatographic conditions. The study used adsorption (NPTLC) and partition (RPTLC) thin-layer chromatography in combination with a densitometric analysis.
Wioletta Parys, Alina Pyka, Pyka-Pająk Alina   +2 more
exaly   +4 more sources

Determination of the LOQ in real-time PCR by receiver operating characteristic curve analysis: application to qPCR assays for Fusarium verticillioides and F. proliferatum [PDF]

Analytical and Bioanalytical Chemistry, 2011
Real-time PCR (qPCR) is the principal technique for the quantification of pathogen biomass in host tissue, yet no generic methods exist for the determination of the limit of quantification (LOQ) and the limit of detection (LOD) in qPCR. We suggest using the Youden index in the context of the receiver operating characteristic (ROC) curve analysis for ...
Petr Karlovsky, Karlovsky Petr
exaly   +5 more sources

Comparison of Different Approaches for Calculating LOD and LOQ in an HPLC-Based Analysis Method [PDF]

Pharmaceutical Sciences
Background: Sensitivity in the determination of the drug concentration is critical in pharmaceutical analysis. This research investigates several approaches for determining two sensitivity parameters, the Limit of Detection (LOD) and the Limit of ...
Raha Kaviani
doaj   +2 more sources

Determining the LOD and LOQ in steel alloys analysis using NITON spectrometer

Journal of Physics: Conference Series, 2021
Abstract Low concentrations standards spectrometric analysis using the NITON spectrometer require the LOD and LOQ to be determined from the analytical method along with identification of the sample matrix. The LOD (the smallest quantity of analyte that can be detected but not necessarily quantified) and LOQ (the smallest quantity of ...
A Krummenauer, P R Dias, H M Veit
exaly   +2 more sources

Portable EDXRF spectrometer: determination of linearity, LOD, LOQ, and working range for the analysis of base and precious metals in liquid matrices

Journal of Physics: Conference Series, 2023
Abstract Utilizing a portable energy dispersive X-ray fluorescence (EDXRF) spectrometer and certified reference materials, this study aimed to determine the linearity, limit of detection (LOD), limit of quantification (LOQ), and working range of the method for quantitative analysis of base and precious metals in liquid matrices.
A Krummenauer, L H Lapazin, M P Cenci, H M Veit   +3 more
exaly   +2 more sources

Limit of detection (LQD)/limit of quantitation (LOQ): comparison of the empirical and the statistical methods exemplified with GC-MS assays of abused drugs

Clinical Chemistry, 1994
Abstract The limit of detection (LOD) for any analytical procedure, the point at which analysis is just feasible, may be determined by a statistical approach based on measuring replicate blank (negative) samples or by an empirical approach, consisting of measuring progressively more dilute concentrations of analyte.
D A, Armbruster, M D, Tillman, L M, Hubbs   +2 more
exaly   +3 more sources

VALIDATION OF SPECTROPHOTOMETRIC METHOD TO QUANTIFY QUERCETIN IN THE IN VITRO DISSOLUTION STUDY OF SELF NANO-EMULSIFYING DRUG DELIVERY SYSTEM (SNEDDS)

Jurnal Farmasi Sains dan Praktis, 2022
Quercetin possesses low solubility and decreases oral bioavailability. One way to increase the bioavailability of quercetin is by formulating a self-nanoemulsifying drug delivery system (SNEDDS).
Wildan Khairi Muhtadi, Ferdy Firmansyah, Tiara Tri Agustini, Pricillia Rahayu, Siti Arifah Fitriyanti, Rodhia Ulfa   +5 more
doaj   +1 more source

Simultaneous Analysis of Fenpropimorph and Fenpropimorph Acid in Six Different Livestock Products Using a Single-Sample Preparation Method Followed by Liquid Chromatography–Tandem Mass Spectrometry

Molecules, 2021
Pesticides in livestock products must be measured to ensure food safety. We developed a single-sample preparation method followed by liquid chromatography–tandem mass spectrometry (LC-MS/MS) for simultaneous determination of fenpropimorph and ...
Seon Wook Kim, Da Jung Lim, In Seon Kim
doaj   +1 more source

Structural insights into dsRNA processing by Drosophila Dicer-2–Loqs-PD

Nature, 2022
Abstract Small interfering RNAs (siRNAs) are the key components for RNA interference (RNAi), a conserved RNA-silencing mechanism in many eukaryotes 1,2 . In Drosophila , an RNase III enzyme Dicer-2 (Dcr-2), aided by its cofactor ...
Shichen Su, Jia Wang, Ting Deng, Xun Yuan, Jinqiu He, Nan Liu, Xiaomin Li, Ying Huang, Hong-Wei Wang, Jinbiao Ma   +9 more
openaire   +2 more sources