Results 1 to 10 of about 219,755 (269)

In vivo protein trapping in Drosophila [PDF]

open access: yesBriefings in Functional Genomics and Proteomics, 2003
The deciphering of complete genome sequences has opened a post-genomic proteomics era. While the sequence of many proteins is now known, attention will increasingly focus on the complex interaction networks that regulate their activity, and the analysis of protein distribution in the cell will be crucial to elucidating their function.
openaire   +2 more sources

Cross-Species Interaction between Rapidly Evolving Telomere-Specific Drosophila Proteins. [PDF]

open access: yesPLoS ONE, 2015
Telomere integrity in Drosophila melanogaster is maintained by a putative multisubunit complex called terminin that is believed to act in analogy to the mammalian shelterin complex in protecting chromosome ends from being recognized as sites of DNA ...
Balázs Vedelek   +2 more
doaj   +1 more source

Label-free quantitative proteomic analysis of adult Drosophila heads

open access: yesSTAR Protocols, 2022
Summary: LIR motif-containing proteins (LIRCPs) bind to LDS (LIR motif docking site) of Atg8-family proteins. In this protocol, we describe steps to identify Drosophila LIRCPs, in Atg8a LDS mutants we have created, via label-free quantitative proteomic ...
Yan Zhang, Ioannis P. Nezis
doaj   +1 more source

A Protein Complex Network of Drosophila melanogaster [PDF]

open access: yesCell, 2011
Determining the composition of protein complexes is an essential step toward understanding the cell as an integrated system. Using coaffinity purification coupled to mass spectrometry analysis, we examined protein associations involving nearly 5,000 individual, FLAG-HA epitope-tagged Drosophila proteins.
Guruharsha, K.G.   +23 more
openaire   +2 more sources

Biochemical and functional analysis of Drosophila-sciara chimeric sex-lethal proteins. [PDF]

open access: yesPLoS ONE, 2013
The Drosophila SXL protein controls sex determination and dosage compensation. It is a sex-specific factor controlling splicing of its own Sxl pre-mRNA (auto-regulation), tra pre-mRNA (sex determination) and msl-2 pre-mRNA plus translation of msl-2 mRNA (
María Fernanda Ruiz   +4 more
doaj   +1 more source

Modular structure of the Drosophila Beat protein [PDF]

open access: yesCurrent Biology, 1997
AR Mushegian, Sequana Therapeutic, Inc., 11099 North Torrey Pines Road, La Jolla, California 92037, USA.
Bazan, J.Fernando, Goodman, Corey S.
openaire   +2 more sources

A modular toolset of phiC31-based fluorescent protein tagging vectors for Drosophila

open access: yesFly, 2019
The Drosophila transgenic technology and fluorescent protein fusions are powerful tools to analyze protein expression patterns, subcellular localization and protein dynamics.
Jun Luo, Pingping Shen, Jiong Chen
doaj   +1 more source

A survey of well conserved families of C2H2 zinc-finger genes in Daphnia

open access: yesBMC Genomics, 2010
Background A recent comparative genomic analysis tentatively identified roughly 40 orthologous groups of C2H2 Zinc-finger proteins that are well conserved in "bilaterians" (i.e. worms, flies, and humans).
Bai Yang, Seetharam Arun, Stuart Gary W
doaj   +1 more source

Identification and Investigation of Postsynaptic Density Homologs

open access: yesBioinformatics and Biology Insights, 2008
AMPA receptors are responsible for fast excitatory transmission in the CNS and the trafficking of these receptors has been implicated in LTP and learning and memory. These receptors reside in the postsynaptic density, a network of proteins that links the
Faith L.W. Liebl, David E. Featherstone
doaj   +1 more source

Exploring Strategies for Protein Trapping in Drosophila [PDF]

open access: yesGenetics, 2007
AbstractThe use of fluorescent protein tags has had a huge impact on cell biological studies in virtually every experimental system. Incorporation of coding sequence for fluorescent proteins such as green fluorescent protein (GFP) into genes at their endogenous chromosomal position is especially useful for generating GFP-fusion proteins that provide ...
Ana T, Quiñones-Coello   +10 more
openaire   +2 more sources

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