Frontiers in Oncology, 2013 Drosophila lacks telomerase and fly telomeres are elongated by occasional transposition of three specialized retroelements. Drosophila telomeres do not terminate with GC-rich repeats and are assembled independently of the sequence of chromosome ends ...
Grazia Daniela Raffa +3 more
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A novel human polycomb binding site acts as a functional polycomb response element in Drosophila. [PDF]
PLoS ONE, 2012 Polycomb group (PcG) proteins are key chromatin regulators implicated in multiple processes including embryonic development, tissue homeostasis, genomic imprinting, X-chromosome inactivation, and germ cell differentiation.
Suresh Cuddapah +6 more
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Molecular analysis of core kinetochore composition and assembly in Drosophila melanogaster.
PLoS ONE, 2007 BackgroundKinetochores are large multiprotein complexes indispensable for proper chromosome segregation. Although Drosophila is a classical model organism for studies of chromosome segregation, little is known about the organization of its kinetochores ...
Marcin R Przewloka +8 more
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Proteomic Characterization of Drosophila melanogaster Proboscis
Biology, 2022 Drosophila melanogaster flies use their proboscis to taste and distinguish edible compounds from toxic compounds. With their proboscis, flies can detect sex pheromones at a close distance or by contact. Most of the known proteins associated with probosci’
Enisa Aruçi +3 more
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Drosophila muscleblind codes for proteins with one and two tandem zinc finger motifs. [PDF]
PLoS ONE, 2012 Muscleblind-like proteins, Muscleblind (Mbl) in Drosophila and MBNL1-3 in vertebrates, are regulators of alternative splicing. Human MBNL1 is a key factor in the etiology of myotonic dystrophy (DM), a muscle wasting disease caused by the occurrence of ...
Uwe Irion
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The distribution of GYR- and YLP-like motifs in Drosophila suggests a general role in cuticle assembly and other protein-protein interactions. [PDF]
PLoS ONE, 2010 BACKGROUND: Arthropod cuticle is composed predominantly of a self-assembling matrix of chitin and protein. Genes encoding structural cuticular proteins are remarkably abundant in arthropod genomes, yet there has been no systematic survey of conserved ...
R Scott Cornman
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Label-free quantitative proteomic analysis of adult Drosophila heads
STAR Protocols, 2022 Summary: LIR motif-containing proteins (LIRCPs) bind to LDS (LIR motif docking site) of Atg8-family proteins. In this protocol, we describe steps to identify Drosophila LIRCPs, in Atg8a LDS mutants we have created, via label-free quantitative proteomic ...
Yan Zhang, Ioannis P. Nezis
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Cross-Species Interaction between Rapidly Evolving Telomere-Specific Drosophila Proteins. [PDF]
PLoS ONE, 2015 Telomere integrity in Drosophila melanogaster is maintained by a putative multisubunit complex called terminin that is believed to act in analogy to the mammalian shelterin complex in protecting chromosome ends from being recognized as sites of DNA ...
Balázs Vedelek +2 more
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A modular toolset of phiC31-based fluorescent protein tagging vectors for Drosophila
Fly, 2019 The Drosophila transgenic technology and fluorescent protein fusions are powerful tools to analyze protein expression patterns, subcellular localization and protein dynamics.
Jun Luo, Pingping Shen, Jiong Chen
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Biochemical and functional analysis of Drosophila-sciara chimeric sex-lethal proteins. [PDF]
PLoS ONE, 2013 The Drosophila SXL protein controls sex determination and dosage compensation. It is a sex-specific factor controlling splicing of its own Sxl pre-mRNA (auto-regulation), tra pre-mRNA (sex determination) and msl-2 pre-mRNA plus translation of msl-2 mRNA (
María Fernanda Ruiz +4 more
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