Molecular analysis of core kinetochore composition and assembly in Drosophila melanogaster.
BackgroundKinetochores are large multiprotein complexes indispensable for proper chromosome segregation. Although Drosophila is a classical model organism for studies of chromosome segregation, little is known about the organization of its kinetochores ...
Marcin R Przewloka +8 more
doaj +1 more source
Comparative proteomic profiling reveals molecular characteristics associated with oogenesis and oocyte maturation during ovarian development of Bactrocera dorsalis (Hendel) [PDF]
Time-dependent expression of proteins in ovary is important to understand oogenesis in insects. Here, we profiled the proteomes of developing ovaries from Bactrocera dorsalis (Hendel) to obtain information about ovarian development with particular ...
Wei, Dong +6 more
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Proteomic Characterization of Drosophila melanogaster Proboscis
Drosophila melanogaster flies use their proboscis to taste and distinguish edible compounds from toxic compounds. With their proboscis, flies can detect sex pheromones at a close distance or by contact. Most of the known proteins associated with probosci’
Enisa Aruçi +3 more
doaj +1 more source
Turning gold into 'junk': transposable elements utilize central proteins of cellular networks [PDF]
The numerous discovered cases of domesticated transposable element (TE) proteins led to the recognition that TEs are a significant source of evolutionary innovation.
Abrusán, György +3 more
core +1 more source
Drosophila muscleblind codes for proteins with one and two tandem zinc finger motifs. [PDF]
Muscleblind-like proteins, Muscleblind (Mbl) in Drosophila and MBNL1-3 in vertebrates, are regulators of alternative splicing. Human MBNL1 is a key factor in the etiology of myotonic dystrophy (DM), a muscle wasting disease caused by the occurrence of ...
Uwe Irion
doaj +1 more source
The distribution of GYR- and YLP-like motifs in Drosophila suggests a general role in cuticle assembly and other protein-protein interactions. [PDF]
BACKGROUND: Arthropod cuticle is composed predominantly of a self-assembling matrix of chitin and protein. Genes encoding structural cuticular proteins are remarkably abundant in arthropod genomes, yet there has been no systematic survey of conserved ...
R Scott Cornman
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PROTEIN DIFFERENCES IN DROSOPHILA. I. DROSOPHILA MELANOGASTER [PDF]
ONE electrophoresis affords a simple, rapid technique for comparing and characterizing proteins. It is especially suitable for investigations of genetically altered proteins, and notable results have come from the use of this method in studying hemoglobins (INGRAM 1961 ) and haptoglobins ( CONNELL, DIXON and SMITHIES 1962).
openaire +2 more sources
Cross-Species Interaction between Rapidly Evolving Telomere-Specific Drosophila Proteins. [PDF]
Telomere integrity in Drosophila melanogaster is maintained by a putative multisubunit complex called terminin that is believed to act in analogy to the mammalian shelterin complex in protecting chromosome ends from being recognized as sites of DNA ...
Balázs Vedelek +2 more
doaj +1 more source
Label-free quantitative proteomic analysis of adult Drosophila heads
Summary: LIR motif-containing proteins (LIRCPs) bind to LDS (LIR motif docking site) of Atg8-family proteins. In this protocol, we describe steps to identify Drosophila LIRCPs, in Atg8a LDS mutants we have created, via label-free quantitative proteomic ...
Yan Zhang, Ioannis P. Nezis
doaj +1 more source
The selectivity and specificity of autophagy in drosophila [PDF]
Autophagy is a process of cellular self-degradation and is a major pathway for elimination of cytoplasmic material by the lysosomes. Autophagy is responsible for the degradation of damaged organelles and protein aggregates and therefore plays a ...
Chou +27 more
core +2 more sources

