Results 11 to 20 of about 1,887,784 (306)

Proteomic identification of Drosophila melanogaster male accessory gland proteins, including a pro-cathepsin and a soluble gamma-glutamyl transpeptidase. [PDF]

open access: yes, 2006
Background In Drosophila melanogaster, the male seminal fluid contains proteins that are important for reproductive success. Many of these proteins are synthesised by the male accessory glands and are secreted into the accessory gland lumen, where they ...
Isaac, R. Elwyn   +6 more
core   +5 more sources

Exploring Banana phytosterols (Beta-sitosterol) on tight junction protein (claudin) as anti-urolithiasis contributor in Drosophila: A phyto-lithomic approach

open access: yesInformatics in Medicine Unlocked, 2022
Claudins are a class of transmembrane proteins in the family of tight junction (TJ) proteins. The disrupted functioning of claudins has been found to have a role in urolithiasis (Kidney stones).
Anirudh Gururaj Patil   +4 more
doaj   +1 more source

Subversion of Atypical Mucin Traps by a Spore-Coat Effector Blocks Cellular Immunity in Drosophila. [PDF]

open access: yesAdv Sci (Weinh)
While the entomopathogenic fungus Metarhizium robertsii can evade insect humoral immunity, its subversion of cellular defenses is still elusive. We identify Eac1 as a spore‐coat protein essential for infecting drosophilids by targeting atypical mucins (Sgf1 and Sgf2), which can entrap spores in a gel matrix and thereby facilitate hemocyte encapsulation.
Li S   +7 more
europepmc   +2 more sources

The S-palmitoylome and DHHC-PAT interactome of Drosophila melanogaster S2R+ cells indicate a high degree of conservation to mammalian palmitoylomes.

open access: yesPLoS ONE, 2022
Protein S-palmitoylation, the addition of a long-chain fatty acid to target proteins, is among the most frequent reversible protein modifications in Metazoa, affecting subcellular protein localization, trafficking and protein-protein interactions.
Elena Porcellato   +10 more
doaj   +1 more source

DrosophilaSOCS Proteins [PDF]

open access: yesJournal of Signal Transduction, 2011
The importance of signal transduction cascades such as the EGFR and JAK/STAT pathways for development and homeostasis is highlighted by the high levels of molecular conservation maintained between organisms as evolutionary diverged as fruit flies and humans. This conservation is also mirrored in many of the regulatory mechanisms that control the extent
Stec, W. J., Zeidler, M. P.
openaire   +3 more sources

A multispecies approach for comparing sequence evolution of X-linked and autosomal sites in Drosophila [PDF]

open access: yes, 2008
Population genetics models show that, under certain conditions, the X chromosome is expected to be under more efficient selection than the autosomes.
Vicoso, Beatriz   +2 more
core   +4 more sources

Site-Specific Profiling of N-Glycans in Drosophila melanogaster

open access: yesFrontiers in Bioscience-Landmark, 2023
Background: Drosophila melanogaster is a well-studied and highly tractable genetic model system for deciphering the molecular mechanisms underlying various biological processes.
Fei Zhao   +6 more
doaj   +1 more source

Drosophila Rbp6 is an orthologue of vertebrate Msi-1 and Msi-2, but does not function redundantly with dMsi to regulate germline stem cell behaviour. [PDF]

open access: yesPLoS ONE, 2012
The vertebrate RNA-binding proteins, Musashi-1 (Msi-1) and Musashi-2 (Msi-2) are expressed in multiple stem cell populations. A role for Musashi proteins in preventing stem cell differentiation has been suggested from genetic analysis of the Drosophila ...
Nicole A Siddall   +7 more
doaj   +1 more source

Construction of an alpaca immune antibody library for the selection of nanobodies against Drosophila melanogaster proteins

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
Introduction:Drosophila melanogaster is a model organism for studying developmental biology and human neural disorders. Nanobodies are the variable domains of the heavy chains of camelid heavy-chain antibodies (VHHs) with high affinity to their antigens ...
Jianxiang Qiu   +7 more
doaj   +1 more source

HP1B is a euchromatic Drosophila HP1 homolog with links to metabolism. [PDF]

open access: yesPLoS ONE, 2018
Heterochromatin Protein 1 (HP1) proteins are an important family of chromosomal proteins conserved among all major eukaryotic lineages. While HP1 proteins are best known for their role in heterochromatin, many HP1 proteins function in euchromatin as well.
Benjamin B Mills   +2 more
doaj   +1 more source

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