Distribution of DNA replication proteins in Drosophila cells
BMC Cell Biology, 2007 Background DNA replication in higher eukaryotic cells is organized in discrete subnuclear sites called replication foci (RF). During the S phase, most replication proteins assemble at the RF by interacting with PCNA via a PCNA binding domain (PBD).
Leonhardt Heinrich +2 more
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Construction and analysis of the protein-protein interaction network of visual system in Drosophila [PDF]
Network Biology, 2023 Insects are one of the most widely distributed animals on earth, and their visual systems have strong adaptability, deeply affecting their survival, reproduction, diet, and environmental adaptation.
JiaNing Sun, WenJun Zhang
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Frontiers in Oncology, 2013 Drosophila lacks telomerase and fly telomeres are elongated by occasional transposition of three specialized retroelements. Drosophila telomeres do not terminate with GC-rich repeats and are assembled independently of the sequence of chromosome ends ...
Grazia Daniela Raffa +3 more
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A novel human polycomb binding site acts as a functional polycomb response element in Drosophila. [PDF]
PLoS ONE, 2012 Polycomb group (PcG) proteins are key chromatin regulators implicated in multiple processes including embryonic development, tissue homeostasis, genomic imprinting, X-chromosome inactivation, and germ cell differentiation.
Suresh Cuddapah +6 more
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Molecular analysis of core kinetochore composition and assembly in Drosophila melanogaster.
PLoS ONE, 2007 BackgroundKinetochores are large multiprotein complexes indispensable for proper chromosome segregation. Although Drosophila is a classical model organism for studies of chromosome segregation, little is known about the organization of its kinetochores ...
Marcin R Przewloka +8 more
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Proteomic Characterization of Drosophila melanogaster Proboscis
Biology, 2022 Drosophila melanogaster flies use their proboscis to taste and distinguish edible compounds from toxic compounds. With their proboscis, flies can detect sex pheromones at a close distance or by contact. Most of the known proteins associated with probosci’
Enisa Aruçi +3 more
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Drosophila muscleblind codes for proteins with one and two tandem zinc finger motifs. [PDF]
PLoS ONE, 2012 Muscleblind-like proteins, Muscleblind (Mbl) in Drosophila and MBNL1-3 in vertebrates, are regulators of alternative splicing. Human MBNL1 is a key factor in the etiology of myotonic dystrophy (DM), a muscle wasting disease caused by the occurrence of ...
Uwe Irion
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PROTEIN DIFFERENCES IN DROSOPHILA. I. DROSOPHILA MELANOGASTER [PDF]
Genetics, 1963 ONE electrophoresis affords a simple, rapid technique for comparing and characterizing proteins. It is especially suitable for investigations of genetically altered proteins, and notable results have come from the use of this method in studying hemoglobins (INGRAM 1961 ) and haptoglobins ( CONNELL, DIXON and SMITHIES 1962).
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Searching for Drosophila Dsn1 kinetochore protein [PDF]
Cell Cycle, 2009 The Mis12/MIND kinetochore complex is composed of 4 subunits of which the Dsn1 protein is a crucial component in all organisms where it has been identified. In Caenorhabditis elegans, depletion of Dsn1 results in a so-called "kinetochore null" phenotype, hence Dsn1's alternative name KNL3.
Przewloka, Marcin +2 more
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The distribution of GYR- and YLP-like motifs in Drosophila suggests a general role in cuticle assembly and other protein-protein interactions. [PDF]
PLoS ONE, 2010 BACKGROUND: Arthropod cuticle is composed predominantly of a self-assembling matrix of chitin and protein. Genes encoding structural cuticular proteins are remarkably abundant in arthropod genomes, yet there has been no systematic survey of conserved ...
R Scott Cornman
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