Results 1 to 10 of about 3,111,959 (339)

RNA-binding proteins in bacteria [PDF]

Nature Reviews Microbiology, 2018
RNA-binding proteins (RBPs) are central to most if not all cellular processes, dictating the fate of virtually all RNA molecules in the cell. Starting with pioneering work on ribosomal proteins, studies of bacterial RBPs have paved the way for molecular studies of RNA-protein interactions.
Erik Holmqvist, Jörg Vogel
semanticscholar   +6 more sources

Guardian of Genetic Messenger-RNA-Binding Proteins [PDF]

Biomolecules, 2016
RNA in cells is always associated with RNA-binding proteins that regulate all aspects of RNA metabolism including RNA splicing, export from the nucleus, RNA localization, mRNA turn-over as well as translation. Given their diverse functions, cells express
Antje Anji, Meena Kumari
doaj   +7 more sources

RNA-binding proteins [PDF]

WormBook, 2006
The C. elegans genome encodes many RNA-binding proteins (RBPs) with diverse functions in development, indicative of extensive layers of post-transcriptional control of RNA metabolism. A number of C. elegans RBPs have been identified by forward or reverse
Lee, Min\u27Ho, Schedl, Tim
core   +6 more sources

RNA binding proteins in osteoarthritis

Frontiers in Cell and Developmental Biology, 2022
Osteoarthritis (OA) is a common chronic degenerative joint disease worldwide. The pathological features of OA are the erosion of articular cartilage, subchondral bone sclerosis, synovitis, and metabolic disorder.
Qian Yi, Qian Yi, Qian Yi, Zhenhan Deng, Jiaji Yue, Jinglong He, Jianyi Xiong, Wei Sun, Weichao Sun, Weichao Sun   +9 more
doaj   +3 more sources

RNA-binding proteins in tumor progression

Journal of Hematology & Oncology, 2020
RNA-binding protein (RBP) has a highly dynamic spatiotemporal regulation process and important biological functions. They are critical to maintain the transcriptome through post-transcriptionally controlling the processing and transportation of RNA ...
Hai Qin, Haiwei Ni, Yichen Liu, Yaqin Yuan, Tao Xi, Xiaoman Li, Lufeng Zheng   +6 more
doaj   +2 more sources

RNA-Binding Proteins in Cardiomyopathies

Journal of Cardiovascular Development and Disease
The post-transcriptional regulation of gene expression plays an important role in heart development and disease. Cardiac-specific alternative splicing, mediated by RNA-binding proteins, orchestrates the isoform switching of proteins that are essential ...
De-Li Shi
doaj   +4 more sources

The RNA Binding Specificity of Human APOBEC3 Proteins Resembles That of HIV-1 Nucleocapsid. [PDF]

PLoS Pathogens, 2016
The APOBEC3 (A3) cytidine deaminases are antiretroviral proteins, whose targets include human immunodeficiency virus type-1 (HIV-1). Their incorporation into viral particles is critical for antiviral activity and is driven by interactions with the RNA ...
Ashley York, Sebla B Kutluay, Manel Errando, Paul D Bieniasz   +3 more
doaj   +5 more sources

RNA-binding proteins as versatile metabolic regulators [PDF]

npj Metabolic Health and Disease
Metabolic shifts are a hallmark of numerous biological processes, including the differentiation of stem cells along a specific lineage and the activation of diverse cell types, such as immune cells.
Ellie Koletsou, Ina Huppertz
doaj   +2 more sources

The role of disorder in RNA binding affinity and specificity [PDF]

Open Biology, 2020
Most RNA-binding modules are small and bind few nucleotides. RNA-binding proteins typically attain the physiological specificity and affinity for their RNA targets by combining several RNA-binding modules.
Diana S. M. Ottoz, Luke E. Berchowitz
doaj   +1 more source

RNA binding proteins in MLL-rearranged leukemia

Experimental Hematology & Oncology, 2022
RNA binding proteins (RBPs) have recently emerged as important post-transcriptional gene expression regulators in both normal development and disease.
Tiffany M. Tran, Dinesh S. Rao
doaj   +1 more source