Results 1 to 10 of about 2,650,258 (157)

A framework for the exploration of subcellular compartmentalization of RNA-binding proteins [PDF]

Nature Communications
The ability of RNA-binding proteins to form complexes with other biomolecules underpins a broad range of structural properties and functions. Understanding the subcellular distribution of RNA-binding proteins and their interacting partners in the steady ...
Xiangpeng Guo, Jieyi Hu, Shahzina Kanwal, Jianwen Yuan, Muqddas Tariq, Jingxia Zheng, Mingwei Sun, Yuanyuan Lu, Jingjing Wang, Mengling Jiang, Aiping Wang, Alvaro Castells-Garcia, Xiyuan Zheng, Bin Peng, Dongye Wang, Xiaofeng Wei, Tao Yang, Giacomo Volpe, Liang Wu, Md. Abdul Mazid, Wenjuan Li, Yiwei Lai, Dajiang Qin, Francesca Aguilo, Yu Zhou, Chuanyu Liu, Maria Pia Cosma, Xingzhi Xu, Emma Lundberg, Jan Mulder, Andrew P. Hutchins, Patrick H. Maxwell, Luciano Di Croce, Xiaofei Zhang, Miguel A. Esteban, Yuan Lv   +35 more
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A census of human RNA-binding proteins

Nature Reviews Genetics, 2014
Post-transcriptional gene regulation (PTGR) concerns processes involved in the maturation, transport, stability and translation of coding and non-coding RNAs. RNA-binding proteins (RBPs) and ribonucleoproteins coordinate RNA processing and PTGR.
Markus Hafner, Thomas Tuschl, Stefanie Gerstberger   +2 more
exaly   +2 more sources

A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins

Cell, 2018
SUMMARY Proteins such as FUS phase separate to form liquid-like condensates that can harden into less dynamic structures. However, how these properties emerge from the collective interactions of many amino acids remains largely unknown.
Alex Holehouse, Jie Wang, Regis Lemaitre   +2 more
exaly   +2 more sources

RNA-Binding Proteins Tia-1 and Tiar Link the Phosphorylation of Eif-2α to the Assembly of Mammalian Stress Granules

Journal of Cell Biology, 1999
In response to environmental stress, the related RNA-binding proteins TIA-1 and TIAR colocalize with poly(A)+ RNA at cytoplasmic foci that resemble the stress granules (SGs) that harbor untranslated mRNAs in heat shocked plant cells (Nover et al.
Paul Anderson, Anderson Paul
exaly   +2 more sources

RNA-binding proteins in tumor progression

Journal of Hematology & Oncology, 2020
RNA-binding protein (RBP) has a highly dynamic spatiotemporal regulation process and important biological functions. They are critical to maintain the transcriptome through post-transcriptionally controlling the processing and transportation of RNA ...
Hai Qin, Haiwei Ni, Yichen Liu, Yaqin Yuan, Tao Xi, Xiaoman Li, Lufeng Zheng   +6 more
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Context-dependent control of alternative splicing by RNA-binding proteins

Nature Reviews Genetics, 2014
Sequence-specific RNA-binding proteins (RBPs) bind to pre-mRNA to control alternative splicing, but it is not yet possible to read the 'splicing code' that dictates splicing regulation on the basis of genome sequence.
Xiang-Dong Fu, Manuel Ares, Fu Xiang-Dong   +2 more
exaly   +2 more sources

Comparative genomic analysis of RNA-binding proteins across some drug resistant and sensitive Staphylococcus aureus [PDF]

Applied Microbiology and Biotechnology
The adaptability and persistence of Staphylococcus aureus in diverse host environments may be influenced by its genetic repertoire, including RNA-binding proteins (RBPs).
Magda M. Awad, Yehia A. Osman, Mohamed Abdelmoteleb   +2 more
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RNA-Binding Proteins: Splicing Factors and Disease

Biomolecules, 2015
Pre-mRNA splicing is mediated by interactions of the Core Spliceosome and an array of accessory RNA binding proteins with cis-sequence elements. Splicing is a major regulatory component in higher eukaryotes.
Alger M. Fredericks, Kamil J. Cygan, Brian A. Brown, William G. Fairbrother   +3 more
doaj   +3 more sources

Regulation of RNA-binding proteins by small biomolecules [PDF]

Nature Reviews Molecular Cell Biology
Douglas Porter, Weili Miao, Paul Khavari   +2 more
exaly   +2 more sources

RNA binding proteins in osteoarthritis

Frontiers in Cell and Developmental Biology, 2022
Osteoarthritis (OA) is a common chronic degenerative joint disease worldwide. The pathological features of OA are the erosion of articular cartilage, subchondral bone sclerosis, synovitis, and metabolic disorder.
Qian Yi, Qian Yi, Qian Yi, Zhenhan Deng, Jiaji Yue, Jinglong He, Jianyi Xiong, Wei Sun, Weichao Sun, Weichao Sun   +9 more
doaj   +1 more source