Results 31 to 40 of about 2,650,407 (299)
Identification of RNA-binding Proteins
Bio-Protocol, 2016 This protocol describes the extraction of RNA-binding proteins (RBPs) from cell lysates. In order to pull down target RBPs, 5-bromo-UTP (BrUTP)-incorporated RNA probes are used, which are generated by in vitro transcription.
Kazuya Masuda, Tadamitsu Kishimoto
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The RNA-Binding Motif Protein Family in Cancer: Friend or Foe?
Frontiers in Oncology, 2021 The RNA-binding motif (RBM) proteins are a class of RNA-binding proteins named, containing RNA-recognition motifs (RRMs), RNA-binding domains, and ribonucleoprotein motifs.
Zhigang Li +6 more
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RNA-binding Proteins in Regulating mRNA Stability and Translation: Roles and Mechanisms in Cancer
Seminars in Cancer Biology, 2022 RNA-binding proteins (RBPs) are key players in cellular physiology through posttranscriptional regulation of the expression of target RNA transcripts.
Wei Li, Xiaolan Deng, Jianjun Chen
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RNA‐binding properties of hnRNP proteins [PDF]
European Journal of Biochemistry, 1988 The RNA‐binding properties of the hnRNP monoparticle proteins were examined using a renaturing blotting procedure. All ‘core’ proteins are able to bind single‐stranded nucleic acids, probably not sequence‐specific. The core proteins C1 and, in one case A2 and B2, are able to bind nucleic acids which are double‐stranded or which show a high degree of ...
Schenkel, J. +3 more
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Stress granules, RNA-binding proteins and polyglutamine diseases: too much aggregation?
Cell Death and Disease, 2021 Stress granules (SGs) are membraneless cell compartments formed in response to different stress stimuli, wherein translation factors, mRNAs, RNA-binding proteins (RBPs) and other proteins coalesce together.
Adriana Marcelo +4 more
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Nature Cell Biology, 2020 Traditionally viewed as an autodigestive pathway, autophagy also facilitates cellular secretion; however, the mechanisms underlying these processes remain unclear.
Andrew M. Leidal +16 more
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The IGF2BP family of RNA binding proteins links epitranscriptomics to cancer.
Seminars in Cancer Biology, 2022 RNA binding proteins that act at the post-transcriptional level display a richness of mechanisms to modulate the transcriptional output and respond to changing cellular conditions. The family of IGF2BP proteins recognize mRNAs modified by methylation and
Deepthi Ramesh-Kumar, S. Guil
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Formation and Maturation of Phase Separated Liquid Droplets by RNA Binding Proteins
Molecules and Cells, 2015 Eukaryotic cells possess numerous dynamic membrane-less organelles, RNP granules, enriched in RNA and RNA binding proteins containing disordered regions.
Yuan Lin +3 more
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RNA buffers the phase separation behavior of prion-like RNA-binding proteins
Science, 2018 RNA and membraneless organelles Membraneless compartments can form in cells through liquidliquid phase separation (see the Perspective by Polymenidou). But what prevents these cellular condensates from randomly fusing together?
Shovamayee Maharana +16 more
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Biomolecules, 2020 Spatiotemporal translational regulation plays a key role in determining cell fate and function. Specifically, in neurons, local translation in dendrites is essential for synaptic plasticity and long-term memory formation.
Rie Ohashi, Nobuyuki Shiina
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