Results 1 to 10 of about 1,319,345 (265)

RNA-Binding Profiles of CKAP4 as an RNA-Binding Protein in Myocardial Tissues [PDF]

open access: yesFrontiers in Cardiovascular Medicine, 2021
Background: Pathological tissue remodeling such as fibrosis is developed in various cardiac diseases. As one of cardiac activated-myofibroblast protein markers, CKAP4 may be involved in this process and the mechanisms have not been explored.Methods: We ...
Hong Zhu   +7 more
doaj   +3 more sources

The role of disorder in RNA binding affinity and specificity [PDF]

open access: yesOpen Biology, 2020
Most RNA-binding modules are small and bind few nucleotides. RNA-binding proteins typically attain the physiological specificity and affinity for their RNA targets by combining several RNA-binding modules.
Diana S. M. Ottoz, Luke E. Berchowitz
doaj   +1 more source

The RNA-Binding Motif Protein Family in Cancer: Friend or Foe?

open access: yesFrontiers in Oncology, 2021
The RNA-binding motif (RBM) proteins are a class of RNA-binding proteins named, containing RNA-recognition motifs (RRMs), RNA-binding domains, and ribonucleoprotein motifs.
Zhigang Li   +6 more
doaj   +1 more source

Research progress of RNA binding motif protein family-mediated alternative splicing in cardiomyopathy [PDF]

open access: yesJichu yixue yu linchuang, 2022
RNA binding motif protein (RBM) is a type of RNA binding protein, which contains RNA recognition motif, RNA binding motif and ribo-nucleo-protein motif.
LIU Shu, DING Hong, ZHAO Ke-xin, BAI Feng, ZHANG Xiao-wei
doaj   +1 more source

Positional motif analysis reveals the extent of specificity of protein-RNA interactions observed by CLIP

open access: yesGenome Biology, 2022
Background Crosslinking and immunoprecipitation (CLIP) is a method used to identify in vivo RNA–protein binding sites on a transcriptome-wide scale.
Klara Kuret   +4 more
doaj   +1 more source

Computational evolution of an RNA-binding protein towards enhanced oxidized-RNA binding

open access: yesComputational and Structural Biotechnology Journal, 2020
The oxidation of RNA has been implicated in the development of many diseases. Among the four ribonucleotides, guanosine is the most susceptible to oxidation, resulting in the formation of 8-oxo-7,8-dihydroguanosine (8-oxoG). Despite the limited knowledge
Juan C. Gonzalez-Rivera   +9 more
doaj   +1 more source

Classifying RNA-binding proteins based on electrostatic properties. [PDF]

open access: yesPLoS Computational Biology, 2008
Protein structure can provide new insight into the biological function of a protein and can enable the design of better experiments to learn its biological roles.
Shula Shazman, Yael Mandel-Gutfreund
doaj   +1 more source

Data of protein-RNA binding sites

open access: yesData in Brief, 2017
Despite the increasing number of protein-RNA complexes in structure databases, few data resources have been made available which can be readily used in developing or testing a method for predicting either protein-binding sites in RNA sequences or RNA ...
Wook Lee   +3 more
doaj   +1 more source

Possible Involvement of the Phloem Lectin in Long-Distance Viroid Movement

open access: yesMolecular Plant-Microbe Interactions, 2001
Incubation with cucumber phloem exudate in vitro results in a dramatic decrease in the electrophoretic mobility of Hop stunt viroid. UV cross-linking and a combination of size exclusion and ion exchange chromatography indicate that this phenomenon ...
R. A. Owens, M. Blackburn, B. Ding
doaj   +1 more source

Crimean-Congo hemorrhagic fever virus nucleocapsid protein has dual RNA binding modes. [PDF]

open access: yesPLoS ONE, 2017
Crimean Congo hemorrhagic fever, a zoonotic viral disease, has high mortality rate in humans. There is currently no vaccine for Crimean Congo hemorrhagic fever virus (CCHFV) and chemical interventions are limited.
Subbiah Jeeva   +4 more
doaj   +1 more source

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