Results 11 to 20 of about 1,873,837 (361)

RNA-binding proteins in bacteria [PDF]

open access: yesNature Reviews Microbiology, 2018
RNA-binding proteins (RBPs) are central to most if not all cellular processes, dictating the fate of virtually all RNA molecules in the cell. Starting with pioneering work on ribosomal proteins, studies of bacterial RBPs have paved the way for molecular studies of RNA-protein interactions.
Erik Holmqvist, Jörg Vogel
openaire   +5 more sources

Chemoproteomic capture of RNA binding activity in living cells

open access: yesNature Communications, 2023
Proteomic methods for RNA interactome capture (RIC) rely principally on crosslinking native or labeled cellular RNA to enrich and investigate RNA-binding protein (RBP) composition and function in cells.
Andrew J. Heindel   +10 more
doaj   +1 more source

Data of protein-RNA binding sites

open access: yesData in Brief, 2017
Despite the increasing number of protein-RNA complexes in structure databases, few data resources have been made available which can be readily used in developing or testing a method for predicting either protein-binding sites in RNA sequences or RNA ...
Wook Lee   +3 more
doaj   +1 more source

Molecular principles underlying dual RNA specificity in the Drosophila SNF protein [PDF]

open access: yes, 2018
The first RNA recognition motif of the Drosophila SNF protein is an example of an RNA binding protein with multi-specificity. It binds different RNA hairpin loops in spliceosomal U1 or U2 small nuclear RNAs, and only in the latter case requires the ...
DeKoster, Gregory T   +4 more
core   +3 more sources

Possible Involvement of the Phloem Lectin in Long-Distance Viroid Movement

open access: yesMolecular Plant-Microbe Interactions, 2001
Incubation with cucumber phloem exudate in vitro results in a dramatic decrease in the electrophoretic mobility of Hop stunt viroid. UV cross-linking and a combination of size exclusion and ion exchange chromatography indicate that this phenomenon ...
R. A. Owens, M. Blackburn, B. Ding
doaj   +1 more source

Real-time assembly of ribonucleoprotein complexes on nascent RNA transcripts. [PDF]

open access: yes, 2018
Cellular protein-RNA complexes assemble on nascent transcripts, but methods to observe transcription and protein binding in real time and at physiological concentrations are not available.
Duss, Olivier   +5 more
core   +2 more sources

Crimean-Congo hemorrhagic fever virus nucleocapsid protein has dual RNA binding modes. [PDF]

open access: yesPLoS ONE, 2017
Crimean Congo hemorrhagic fever, a zoonotic viral disease, has high mortality rate in humans. There is currently no vaccine for Crimean Congo hemorrhagic fever virus (CCHFV) and chemical interventions are limited.
Subbiah Jeeva   +4 more
doaj   +1 more source

Mechanism of RNA recognition by a Musashi RNA-binding protein

open access: yesCurrent Research in Structural Biology, 2022
The Musashi RNA-binding proteins (RBPs) regulate translation of target mRNAs and maintenance of cell stemness and tumorigenesis. Musashi-1 (MSI1), long considered as an intestinal and neural stem cell marker, has been more recently found to be over ...
Jinan Wang   +4 more
doaj   +1 more source

RNA-binding protein CPEB1 remodels host and viral RNA landscapes. [PDF]

open access: yes, 2016
Host and virus interactions occurring at the post-transcriptional level are critical for infection but remain poorly understood. Here, we performed comprehensive transcriptome-wide analyses revealing that human cytomegalovirus (HCMV) infection results in
Aigner, Stefan   +17 more
core   +2 more sources

γ-AApeptides bind to RNA by mimicking RNA-binding proteins [PDF]

open access: yesOrganic & Biomolecular Chemistry, 2011
The interactions between proteins and RNAs are of vital importance for many cellular processes, including transcription and processing of RNA, translation, and viral infections. Here we report an γ-AApeptide that can mimic HIV-1 Tat protein and bind to TAR RNAs of HIV and BIV with nanomolar affinity, comparable to that of the RNA-binding fragment of ...
Youhong, Niu   +4 more
openaire   +2 more sources

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